Instagram sisters raise neurodiversity awareness
Iveta Pudilova, 24, discovered she was neurodivergent after sister Vera was diagnosed with autism.
"I grew up non-verbal. I couldn't speak until I was about five years old and even now I experience verbal shutdown. So verbal communication can be a really difficult challenge," Iveta said.
In 2019, Vera started documenting her experiences through drawings and reflections on Instagram. Iveta helped and the Birmingham sisters went on to found the National Neurodiversity Training company last year.
By May, the company had delivered neurodiversity training to seven organisations and 350 people, helping them to understand how to better support employees.
Neurodivergence is an umbrella term that includes a number of conditions including autism spectrum disorder, attention-deficit hyperactivity disorder and dyslexia.
Iveta said her sister Vera's Instagram reflections had not been intended to go viral, but her take on life gained unexpected traction.
She explained her sister was "a very creative person" who made "content illustrations about her experience of being diagnosed... to connect with other autistic people".
Iveta joined her and added: "We started an e-commerce [initiative], selling communication products like badges and cards, because a lot of neurodivergent people are non verbal."
'More productive'
Badges and cards have helped neurodivergent people express themselves in public.
One design reads: "I wear noise-cancelling headphones but I can still hear you."
Iveta said they had started e-commerce work "to empower other neurodivergent people".
However, she added "the lack of neurodiversity awareness and support is impacting everyone, including companies, and so we transitioned to delivering neurodiversity training".
Their company now works with organisations including the NHS and is behind training delivered in tech firms, universities and local government.
One project, in partnership with Birmingham Newman University and the NHS, involved training psychological and wellbeing practitioners to better support autistic patients.
'Looking to leave'
"What we found is that neurodiverse teams are about 30% more productive when they have the right support," Iveta said.
"But 50% of neurodivergent staff are... looking to leave their employer because of a lack of support."
She said in the work with the NHS, they had addressed "diagnostic bias", which she explained was essentially when a practitioner diagnosing someone "might have personal biases".
The company was invited to deliver staff training "on recognising their own biases, addressing them, but then also tailoring their therapy services and support to their autistic patients".
Iveta added: "In the last year we've seen kind of the corporate world take up neurodiversity a lot more because there's more demand both internally, and [from] society pressures."
Follow BBC Birmingham on BBC Sounds, Facebook, X and Instagram.
The young entrepreneurs embracing neurodiversity
'Neurodiversity awareness growing in Guernsey'
Neurodiversity Celebration Week 2025: What is it all about?
Film about neurodivergency tackles 'assumptions'
Related internet links
National Neurodiversity Training
Hashtags

Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles


Medscape
12 minutes ago
- Medscape
Can Preventing, Treating Herpes Reduce Dementia Risk?
Mounting evidence points to a connection between dementia and common herpes virus infections, particularly herpes simplex virus type 1 (HSV-1), which causes cold sores, and varicella zoster virus (VZV), the cause of chickenpox and shingles. Multiple studies have shown that individuals with a history of these infections face a higher risk for dementia, including Alzheimer's disease (AD). What was once a fringe hypothesis has gained traction, as a growing body of research points to these viruses as major factors in Alzheimer's and other dementias. 'There is now quite a lot of evidence obtained by a variety of methods which suggests that this virus is really a major factor in Alzheimer's disease. And the weight of the evidence supports a causal role,' Ruth Itzhaki, MSc, PhD, visiting professor, The Oxford Institute of Population Aging, Oxford, England, told Medscape Medical News . Itzhaki was one of the first to hypothesize there was a potential connection between the herpes virus and AD and has spent much of her career investigating the link. These pathogens may act as 'under-recognized drivers of neurodegeneration. They can hide in the nervous system and reactivate later in life, each flare-up potentially inflicting cumulative damage that accelerates cognitive decline,' Shaheen Lakhan, MD, PhD, neurologist and researcher based in Miami told Medscape Medical News . One early clue came decades ago, when Itzhaki and colleagues discovered HSV-1 DNA in the brains of patients with AD, most notably in carriers of the apolipoprotein E epsilon 4 ( APOE ε4 ) gene, a known genetic risk factor for the disease. 'The virus and the gene may be working in tandem — a synergy where a latent viral infection 'flips the switch' on a genetic vulnerability,' Lakhan said. Supporting a potential causal role, Itzhaki's team has since demonstrated that HSV-1 infection of cultured human neuronal cells induces the accumulation of amyloid-beta and phosphorylated tau — the primary components of amyloid plaques and neurofibrillary tangles in AD. The treatment with antiviral agents significantly reduced both these pathological markers and cell death. Are All Herpes Viruses Tied to Dementia? While research strongly suggests a link between certain herpes viruses and an increased risk for dementia, not all herpes viruses have been implicated. HSV-1 and VZV have been more consistently linked to an increased risk for dementia, including AD. While some studies suggest a possible association with HSV-2 (genital herpes), the evidence is less conclusive than that for HSV-1 and VZV. Other herpes viruses, like cytomegalovirus, have not shown a strong or consistent association with an increased dementia risk in most studies. Research has also suggested that individuals with both HSV-1 and VZV infections may face an elevated, compounded risk. In one study, patients co-infected with HSV and VZV had a hazard ratio of 1.57 for developing dementia, whereas those with HSV-1 alone had a hazard ratio of 1.38 and those with VZV alone had a hazard ratio of 1.41. Itzhaki explained that multiple biologically plausible mechanisms — supported by various studies — may explain the link between herpes virus infections and an increased risk for dementia. For instance, herpes viruses can trigger chronic inflammation in the brain, a critical factor in neurodegeneration. Additionally, HSV-1 may promote amyloid plaque formation and influence tau phosphorylation, as previously noted. The damage and risk occur as a result of reactivation of dormant HSV-1 in the brain after various types of damage, Itzhaki noted. One recent study showed reactivation of dormant HSV-1 after mild brain injury or after cumulative general infections may drive neurodegenerative diseases by triggering pathological changes including accumulation of beta-amyloid and phosphorylated tau. 'The notion that a virus many of us carry could be stoking neurodegeneration is provocative, but the science behind it is becoming increasingly difficult to ignore. The past few years have delivered especially compelling data to support this viral link,' said Lakhan. Antivirals, Vaccines Preventive? Some studies suggest antiviral medications used to treat herpes infections and vaccination against VZV could potentially reduce the dementia risk. For example, one recent Taiwanese cohort study showed that symptomatic HSV-1 infection was associated with nearly a threefold increased risk of developing dementia. Antiherpetic medication reduced the risk by 90%. However, a study of US veterans showed no link between HSV infection and increased dementia risk. Nonetheless, similar to the Taiwanese study, antiherpetic medication was associated with a protective effect against dementia. Separately, in a matched case-control study of nearly 700,000 older adults, HSV-1 was more common in those with AD, and antiviral therapy for HSV-1 was associated with a lower risk of developing AD. Yet in the VALAD clinical trial, valacyclovir therapy did not change the course of disease in older adults with early AD or mild cognitive impairment and antibodies revealing previous herpes infections — mainly HSV-1. 'Our trial suggests antivirals that target herpes are not effective in treating early Alzheimer's and cannot be recommended to treat such patients with evidence of prior HSV infection,' lead investigator, Davangere P. Devanand, MD, professor of psychiatry and neurology and director of Geriatric Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, in New York City, said in a news release. 'We do not know if long-term antiviral medication treatment following herpes infection can prevent Alzheimer's because prospective controlled trials have not been conducted,' Devanand said. On the other hand, data suggest that vaccination against VZV may offer protection against cognitive decline. In a landmark UK study that leveraged a unique vaccine rollout policy in Wales and analyzed health records of over 280,000 older adults, the receipt of the live-attenuated shingles vaccine was associated with approximately a 20% reduction in the risk of developing dementia over 7 years. Lakhan said this study offers 'one of the strongest pieces of evidence yet that preventing varicella-zoster reactivation (shingles) may translate into protecting the brain. In an era when we have few effective dementia preventives, the possibility that something as simple as a vaccine or antiviral could reduce risk by 20% or more is galvanizing.' What to Tell Patients Lakhan believes 'the herpes-dementia connection can no longer be dismissed as coincidence; it demands our attention and further investigation.' He said physicians should be ready to address it in conversations with patients. 'It's increasingly common for older patients, and their families, to ask, 'Doc, I heard that cold sores or shingles might cause Alzheimer's — should I be worried?' Lakhan said. The answer should be 'balanced. We can't say herpes viruses cause Alzheimer's with absolute certainty, but we can say there's enough evidence to suggest they're contributing factors — and that taking steps to mitigate these infections is wise,' Lakhan said. He added that he now routinely recommends the shingles vaccine to all eligible patients not only to prevent a painful rash but also as a potential investment in their long-term brain health. 'There's little downside and plenty of upside to keeping these viruses at bay,' he added. He also advised 'prompt and aggressive' treatment of herpes outbreaks and prescribes antivirals for recurrent HSV-1 flares. Some researchers, he said, are investigating whether chronic suppressive antiviral therapy might help delay dementia in high-risk individuals, though it's too early to recommend this as standard practice. At present, Lakhan advises against prescribing daily antivirals solely for dementia prevention outside of clinical trials. However, for patients with frequent herpes reactivations or those who carry the APOE ε4 gene alongside a strong family history, he maintains a low threshold for treatment and emphasizes counseling on viral prevention. Itzhaki noted that several surveys suggest antivirals may offer some protection against dementia. Taking antivirals in late middle age — when the immune system weakens — could be considered for individuals infected with HSV who also carry genetic risk factors. Lakhan, said 'the bottom line for practitioners is clear — encourage shingles vaccination, stay vigilant against chronic herpes infections, and consider that maintaining viral suppression might become part of our toolkit for preserving brain health.'
Yahoo
40 minutes ago
- Yahoo
Trividia Health introduces 5-Bevel Pen Needles in UK
Trividia Health UK has launched the TRUEplus 5-Bevel Pen Needles in the country, marking the product's first entry outside the US. The new line of insulin pen needles is said to provide healthcare professionals with a range of needle gauges and sizes to offer their diabetic patients, emphasising cost-effectiveness. The needles are engineered for enhanced comfort and are available in sizes, including 31 Gauge 5mm; 6mm; and 8mm, as well as 32 Gauge 4mm. Their design aims to enhance the injection experience and encourage individual compliance. Trividia's TRUEplus 5-bevel pen needles are said to offer an enhanced alternative to the older 3-bevel needle designs, which the company reports are less comfortable and may be expensive for patients. The TRUEplus brand, along with other retail pharmacy brand names, has distributed the 5-bevel pen needles across the US. Trividia Health CEO and president Jonathan Chapman said: 'Providing accessibility to a range of products for patients to confidently manage their diabetes is a priority for us at Trividia Health. 'Having the TRUEplus 5-Bevel Pen Needles as registered products in the UK allows healthcare providers the option to provide patients with high-quality, low-cost pen needles to manage their diabetes.' The company has expanded its diabetes care portfolio with the TRUENESS blood glucose monitoring system, launched in September 2024. TRUENESS offers cost-effective blood glucose management with options such as the TRUENESS AIR meter, which connects to the TRUE MANAGER AIR APP via Bluetooth, helping users link their daily activities with blood glucose levels. US-based consumer health and wellness organisation Trividia Health is the parent company of Trividia Health UK. "Trividia Health introduces 5-Bevel Pen Needles in UK" was originally created and published by Medical Device Network, a GlobalData owned brand. The information on this site has been included in good faith for general informational purposes only. It is not intended to amount to advice on which you should rely, and we give no representation, warranty or guarantee, whether express or implied as to its accuracy or completeness. You must obtain professional or specialist advice before taking, or refraining from, any action on the basis of the content on our site. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
an hour ago
- Yahoo
Europe's cannabis pharmaceuticals market matures amid cautious investment
Europe's cannabis pharmaceutical market is far from a gold rush, yet it is emerging as one of the more strategic long-term plays available today. Unlike traditional drug development, which often starts with costly preclinical trials and faces high failure rates, cannabinoid medicines benefit from a rare advantage: millions of patients worldwide already use cannabinoids. This growing body of real-world evidence is helping companies to mitigate early-stage risks and design more efficient clinical trials. GW Pharmaceuticals, acquired by Jazz Pharma for $7.2 billion, is widely cited as a blueprint for end-to-end cannabinoid drug development. The British firm's success with Epidiolex, a CBD-based epilepsy treatment, demonstrated the feasibility of progressing from cultivation through to regulatory approval. In 2024, it raked in about $972.4 million in sales, and GlobalData analysis shows therapy sales may continue their upward trajectory and pull in over $1.3bn by 2030. Today, new entrants can access many of the foundational assets - active pharmaceutical ingredients, regulatory dossiers, manufacturing partnerships that GW painstakingly built, significantly lowering barriers to entry. Emerging players such as MMJ International Holdings and Zynerba Pharmaceuticals are also carving out a niche in cannabinoid-based therapies, targeting neurological disorders. Yet despite clear clinical opportunities across central nervous system (CNS) disorders, chronic pain, multiple sclerosis and cancer, capital remains a sticking point. Public markets remain cautious, and institutional investors largely absent. Instead, growth is being fuelled by family offices and strategic high-net-worth individuals drawn to de-risked licensing models, where companies out-license cannabinoid drugs to big pharma after Phase II or III trials. Some industry experts suggest the future lies in dual-track models that combine rigorous clinical research with the agility afforded by real-world data. A notable shift is underway: as US companies with consumer marketing expertise enter drug development, the blending of consumer branding with pharmaceutical discipline could create enduring competitive advantages. 'We don't have to start from scratch anymore,' said Melissa Sturgess, CEO of Ananda Pharma, during a panel discussion at Cannabis Europa 2025. 'The science is known. The data is building. Now it's about execution.' Lessons from the US: slow growth as a strategic advantage North American investors watching Europe's cannabis sector are bringing with them lessons learned through a market boom-and-bust cycle. Their cautious optimism signals that this next phase will be defined less by hype and more by discipline. 'Europe is five to six years behind the US, and that's actually a good thing,' said Anthony Coniglio, CEO and President of New Lake, a cannabis net lease real estate investment trust. 'It means there's still a chance to do things right.' The US market's rapid growth in the late 2010s, driven by celebrity-backed brands and aggressive retail expansion, also left a trail of bankruptcies and disappointed investors. Europe's more measured pace - built on pharmaceutical-grade standards, medical infrastructure and tighter regulation offers a foundation for long-term stability, though it may try the patience of entrepreneurs. Nonetheless, significant challenges remain. Experts highlighted three key reasons for investor caution: regulatory instability, with shifting rules that complicate long-term planning; ongoing uncertainty around pricing, patient access and supply-demand dynamics; and competition from more established sectors offering superior risk-adjusted returns, especially in today's high-interest rate environment. 'Cannabis doesn't operate in a vacuum,' said Tristan Gervais, managing director of investment firm T Capital. 'We're not just comparing cannabis companies to each other. We're comparing them to every other investment in the portfolio.' The tone of the discussion underscored a market correction: the era of raising capital on a pitch deck and a promise is over. Investors now demand evidence of financial discipline. 'Cash flow is everything,' stressed John Pinto, Soje Capital. 'You have to demonstrate that you can either reach profitability or survive long enough to get there.' This shift reflects a broader recalibration. Cannabis start-ups that once relied on successive funding rounds to fuel rapid growth must now show how they will operate lean, build resilient infrastructure and reduce reliance on external capital. It is no longer about brands or packaging - nor cannabis in the traditional sense. Investors are increasingly drawn to asset-light models focused on technology, logistics, and services rather than cultivation or retail, as well as non-plant-touching infrastructure such as real estate, supply chains, and pharmaceutical compliance. Experts also singled out hemp-derived, low-dose consumer products as an area of interest, particularly those that navigate restrictive THC laws while appealing to wellness-focused consumers. Crucially, companies must present themselves as well-run businesses operating in the cannabis sector, not simply 'cannabis companies.' The investor view For those seeking investment, investors offered a clear checklist: Clarity of purpose: What core problem are you solving, and why now? Operational discipline: Can you demonstrate governance, financial controls, and professional leadership? Scalable model: Is there a path to profitability without overreliance on volatile capital markets? Regulatory compliance: Are you GMP-certified, pharmaceutical-grade, and built for longevity? Capital strategy: Do you have access to future funding, or better yet, can you sustain without it? 'Without answers to these questions, you're not investable right now,' warned William Muecke, Chief Investment Officer of Artemis Growth Partners. Despite the hurdles, the consensus was clear: for those with the right approach, this remains one of the most promising moments in cannabis history. 'If you're raising money, it's tough out there,' Muecke concluded. 'But if you have money, this might be the best time to deploy it. The winners in Europe will be those who build methodically, understand regulation, and treat capital as a precious resource - not a lifeline.' "Europe's cannabis pharmaceuticals market matures amid cautious investment" was originally created and published by Pharmaceutical Technology, a GlobalData owned brand. The information on this site has been included in good faith for general informational purposes only. It is not intended to amount to advice on which you should rely, and we give no representation, warranty or guarantee, whether express or implied as to its accuracy or completeness. You must obtain professional or specialist advice before taking, or refraining from, any action on the basis of the content on our site.