
Singapore to Study Using More TCM Therapies in Public Healthcare
The health ministry has received 18 proposals on treatments that can be adopted and a committee will evaluate the scientific robustness of each of them, Health Minister Ong Ye Kung said Sunday. Some will be implemented in a 'controlled environment' in the city's public healthcare institutions for one to two years, he said, adding that the cost-effectiveness of each treatment will also be studied.
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Yahoo
an hour ago
- Yahoo
Hate Mondays? Science Just Explained Why We All Feel That Way
A new study reveals that the stress many people feel on Mondays is hardwired into our biology, affecting both workers and retirees alike. The 'anxious Monday' effect disrupts critical bodily systems, including cortisol regulation and heart health. Researchers noted a 23% spike in cortisol and a 19% rise in heart attack risk, showing Monday stress can ripple through the entire this: after a restful and rejuvenating weekend, your 6 a.m. alarm starts ringing on the most dreadful day of the week—Monday. Whether you work from home or schlep to the office, Monday morning signals to your brain and body that the work week has arrived. You might wonder whether everyone feels this way, or if there's something unique to your brain chemistry that makes Monday feel as awful as it does. But according to a new study conducted by the University of Hong Kong and published in the Journal of Affective Disorders, it's clear that you're not alone. Researchers found that Monday stress is etched into our biology, and as a society, we're all conditioned to hate that first day of the work week (yes, it even affects retirees!). To learn more, we delved into why Mondays are linked to a heightened sense of anxiety, where those feelings of overwhelm sit in the body, and how they may affect our overall health. The 'anxious Monday' effect was observed in both working folks and retirees, with researchers analyzing data from over 3,500 older adults participating in a longitudinal aging study. 'Mondays act as a cultural 'stress amplifier,'" says professor Tarani Chandola, lead author of the study. "For some older adults, the week's transition triggers a biological cascade that lingers for months. This isn't about work—it's about how deeply ingrained Mondays are in our stress physiology, even after careers end.' The hypothalamic-pituitary-adrenal (HPA) axis, or the collection of glands and hormones that control cortisol, hypertension, insulin, and immunity levels, was found to be uniquely disrupted on Mondays. It's engrained in our human physiology and culture that Mondays are stress amplifiers. Beyond the realization that we're prone to hating Mondays, researchers also analyzed the effects of 'anxious Monday' on our overall health. Key findings included a 23% increase in cortisol levels (found in hair samples), with non-workers affected just as much as working folks, and a 19% increase in heart attacks. Interestingly, the study found that only 23% of the 'anxious Monday' effect is linked to explained causes, mostly perceived anxiety on Mondays, while the other 77% of the effect resulted from an "unexplained component." TL;DR: It's okay to give yourself grace on Mondays, because it's not just pseudo-symptoms causing that dreaded feeling in your gut. Be kind to yourself and others, especially at the start of the week! Read the original article on Real Simple

Vogue
2 hours ago
- Vogue
Best time to take collagen, according to experts
K-dramas are continually teaching me about life. First, there's the incredible skincare and makeup—and now, a much more surprising habit: Collagen supplements, which are shown as a stable in the regimens of the stars morning routines. For me, incorporating collagen into my morning cup of coffee (just like Jennifer Aniston!) has been a total game-changer. So, what is collagen and how does it work? Read on for more about the skin-supporting, body-strengthening supplement that's recommended for anybody over 25 years old. The supplement is popular among all ages for skin protection, improved texture, firmness, and hydration, though experts recommend it for those aged 25 and above. It even benefits your hair and nails, making them stronger. As for the best time to take collagen, consistency in daily intake is key, giving you room for flexibility with the timing. How do collagen supplements work? 'Randomized, controlled trial studies these have shown a significant improvement in a person's overall skin health when taking collagen supplements,' says Dr. Deepthi Atmakuri, dermatologist and founder of Clinica Derm. 'In some cases, it's been seen in less than eight weeks.' While the particles ingested from the supplements don't directly reach the skin, they are broken down in the digestive system into amino acids, which are the building blocks of protein in the body. These amino acids are then absorbed into the bloodstream and can help stimulate the production of new collagen in the body. Dr. Deepthi says you may notice improvements in two to three months, but immediate effects like plumper-looking skin and reduced dullness can present themselves as early as 15 days. When is the best time to take collagen supplements? While collagen supplements don't require a strict schedule, they do require need consistency. 'A regular intake of collagen is most important because your body needs a consistent supply to feel any long-term benefits,' says Dr. Archana Batra, a dietitian and certified diabetes educator. She presents a couple of options for setting daily reminders.


Associated Press
5 hours ago
- Associated Press
JCR Pharmaceuticals Enters License Agreement with Alexion for Proprietary JUST-AAV Capsids to be Used in the Development of Genomic Medicines
HYOGO, Japan--(BUSINESS WIRE)--Jul 8, 2025-- JCR Pharmaceuticals Co., Ltd. (TSE 4552; 'JCR') today announced that it has entered into a license agreement with Alexion, AstraZeneca Rare Disease ('Alexion'), for JCR's new, proprietary JUST-AAV capsids to develop genomic medicines. JUST-AAV encompasses a range of vector types optimized for various target tissues—including liver-sparing, muscle-targeting, and brain-targeting variants—to expand the potential of AAV-based gene therapy. Under the terms of the agreement, Alexion may use the licensed capsids, which are part of the JUST-AAV platform, in up to five of Alexion's genomic medicines programs. JCR will receive an upfront payment from Alexion. JCR is eligible to receive milestone payments of up to USD 225 million related to research and development, and up to USD 600 million related to sales, for a total of up to USD 825 million (approximately JPY 120 billion converted at the exchange rate of JPY 145 to USD), which reflects the aggregate milestones if all five targets are exercised. In addition, JCR is entitled to receive tiered royalties based on net sales. This agreement marks the third partnership between JCR and Alexion, following research collaborations involving J-Brain Cargo ® technology— the first announced in March 2023 for neurodegenerative disease and the second announced in December 2023 for the discovery of oligonucleotide therapeutics. 'I am very pleased to announce the signing of this license agreement for our proprietary AAV capsid platform, JUST-AAV,' said Shin Ashida, Chairman, President and CEO of JCR Pharmaceuticals. 'I believe JUST-AAV has the potential to make a real difference in the development of gene therapies for rare diseases, and I look forward to its application across a broader range of conditions. JCR values its partnership with Alexion, and we are pleased to build on the collaboration we have developed over the years.' The impact of this agreement on JCR's consolidated financial results for the fiscal year ending March 31, 2026, has already been factored into the current earnings forecast. View source version on CONTACT: Investors & Media: JCR Pharmaceuticals Co., Ltd. Corporate Communications [email protected] KEYWORD: JAPAN ASIA PACIFIC INDUSTRY KEYWORD: SCIENCE OTHER SCIENCE BIOTECHNOLOGY RESEARCH PHARMACEUTICAL GENERAL HEALTH HEALTH HEALTH TECHNOLOGY SOURCE: JCR Pharmaceuticals Co., Ltd. Copyright Business Wire 2025. PUB: 07/08/2025 01:58 PM/DISC: 07/08/2025 01:57 PM