
Want to have a baby? UK warns against ‘skinny jabs' like Ozempic, Wegovy as animal tests show potential harm to newborns
The Medicines and Healthcare products Regulatory Agency (MHRA) said popular jabs like Ozempic and Wegovy 'must not be taken during pregnancy, while trying to get pregnant, or during breastfeeding'.
It urged women to use 'effective contraception while taking these medicines and, in some cases, for up to two months between stopping the medicine and trying to get pregnant'.
'Anyone who gets pregnant while using them should speak to their healthcare professional and stop the medicine as soon as possible... because there is not enough safety data to know whether taking the medicine could cause harm to the baby,' it added.
Rebecca Reynolds, a professor of metabolic medicine at the University of Edinburgh, said there was 'hardly any available data from human studies' to know if the weight loss drugs were safe in pregnancy.
'The data from animal studies suggests the potential for harm with low birthweight and skeletal abnormalities, though more evidence is needed to assess if there are risks of taking these drugs in humans,' she added.
The MHRA also warned about the impact of another weight-loss and diabetes injection, Mounjaro, on the effectiveness of oral contraception for people who are overweight.
'Therefore, those taking Mounjaro who are overweight and are using an oral form of contraception are advised to also use a non-oral form of contraception,' it said.
Ying Cheong, a consultant in reproductive medicine at the University of Southampton, called the MHRA's advice 'both timely and necessary'.
'Gastrointestinal side-effects such as vomiting and diarrhoea can impair oral contraceptive absorption, increasing the risk of unintended pregnancy,' he said. — AFP
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Malay Mail
a day ago
- Malay Mail
After two-year Darwin-inspired voyage, young scientists return with climate warning and hope
ROTTERDAM, Aug 2 — After a two-year around-the-world ocean voyage inspired by Charles Darwin, scientists and crew sailed home on a historic vessel into Rotterdam yesterday bearing a warning about climate change—but also a message of hope. The majestic three-masted Oosterschelde, the last remaining vessel from a fleet of Dutch schooners that criss-crossed the globe in the early 20th century, arrived at a welcome befitting a voyage of more than 40,000 nautical miles (74,000 kilometres, 46,000 miles). Ceremonially escorted by more than a dozen vessels ranging from tall ships to steamships, all blaring horns, the Oosterschelde received a 'water cannon salute' from fire service boats, as hundreds waved and cheered from the banks. Like Darwin in 1831, the Oosterschelde departed the British port of Plymouth in August 2023 to embark on a voyage of discovery that took in the major stops explored during the British naturalist's world-changing mission aboard the HMS Beagle. From the Falkland Islands to the southern tips of Africa, South America and Australia, the trip closely shadowed Darwin's voyage that inspired his groundbreaking theory of natural selection described in 'On the Origin of Species'. Aboard the Oosterschelde at various points of the voyage were some of the world's best young conservationists, 100 scientists aged 18-25, selected to study a species also observed by Darwin, himself aged 22 at the time of his trip. Giant tortoises, Chilean dolphins, and howler monkeys were just some of the weird and wonderful creatures the young 'Darwin Leaders' investigated, tracking changes since their appearance in 'Origin of Species' two centuries ago. With 'online classrooms' onboard and slick social media output, the mission also hoped to inspire a new generation around the message: 'Conservation isn't about what we've lost, it's about protecting what we still have.' 'Barely anything left' One of the Darwin Leaders, 23-year-old Lotta Baten, spent a week on the ship and conducted a study into the impact of tourism on forests in Tenerife, Spain. She said only roughly four percent of the forest that Darwin would have seen from the Beagle is still alive today, with much torn down to support the tourism industry. 'There's barely anything left, mainly the strips around the coast,' the Dutch-German scientist told AFP. She said it was 'quite something' to follow in the footsteps of Darwin, but noted that the botanist's legacy is divided, as a European in colonial times. 'He basically explored and discovered things that maybe had already been explored and discovered by people at the places themselves. And then he claimed he discovered them,' said Baten. Science co-ordinator Rolf Schreuder admitted that 'it's not a rosy picture', with habitat loss and climate change all transforming the environment beyond what Darwin would have recognised. 'You see the natural world degrading in many places,' the 55-year-old told AFP. But Schreuder, like many on board, found the mission inspiring rather than depressing. He ran more than 100 local projects during the trip with people seeking to preserve their landscapes. 'We met so many great people that are actually on the ground working on the survival of those species,' he said. He found himself inspired too by the young scientists, 'full of ideas, full of commitment and determination to really make a difference.' 'Do another tour' Crew member Daan van Roosmalen was a boy of 17 when he set sail on the Oosterschelde. He returned to his native Netherlands having just turned 19. 'I've just been to so many places. To the Galapagos Islands, French Polynesia. We went so far away and to then sail back up this river and see the skyline of Rotterdam again is just super special,' he told AFP. He said he hoped the round-the-world voyage completed by scientists and crew his age would send a message to his generation. 'I think it's very important that we keep inspiring young people to look after our world, because we are going to be the ones taking over,' he said. 'So to see all these young conservationists putting so much effort in Mother Earth... I think that should inspire more people to also take care of our planet.' And what of Darwin, the inspiration behind the mission? 'I would say he would have been enthused by his fellow young people taking care of this natural world, which he described so nicely,' said Schreuder. 'I think he would hop on this boat again and do another tour.' — AFP


Malay Mail
a day ago
- Malay Mail
Dusit International signs strategic partnership for hotel development in France
Dusit International and SYDEL formally established Dusit France at a signing ceremony held in Paris. Pictured (from left): Mr Donatien Carratier, Head of Dusit France; Mr Jordan Elbaz, Partner, SYDEL; Mr Gilles Cretallaz, Chief Operating Officer, Dusit International; and Mr David Elgrably, Partner, SYDEL. PARIS, FRANCE - Media OutReach Newswire - 1 August 2025Dusit International, one of Thailand's leading hotel and property development companies, has signed a strategic partnership agreement with SYDEL, a French real estate investment company, to establish– a joint venture created to bring Dusit's unique brand of Thai-inspired gracious hospitality to France for the first SYDEL's local knowledge and operational expertise, the joint venture will focus on identifying opportunities for Dusit Hotels and Resorts, whose portfolio of nine brands spans the lodging spectrum – from affordable lifestyle hotels to full-service luxury being considered for the French market include(Bespoke Luxury),(Wellness Luxury),(Character Luxury),(Upper Upscale),(Lifestyle Upscale),(Upper Midscale),(Lifestyle Midscale), and(Lifestyle Long Stay).Together, Dusit and SYDEL will identify strategic locations, support asset owners with repositioning projects, and introduce innovative hotel concepts focused on delivering memorable guest experiences, championing well-being, and creating long-term sustainable partnership was formalised at an exclusive signing ceremony held on 10 July 2025 in Paris. At the event,, shared the vision forand outlined the group's growth ambitions in the region."We are thrilled to partner with SYDEL to seek opportunities to expand Dusit's footprint and bring our distinctive brand of Thai-inspired gracious hospitality to France – one of the world's most iconic travel destinations," said Mr Cretallaz. "This partnership marks an important milestone in our global expansion strategy, and we are confident that our unique blend of cultural authenticity, innovation, and gracious service will resonate strongly with travellers and developers alike."Dusit's portfolio currently spans 294 properties across 18 countries, including 55 operating under Dusit Hotels and Resorts and 239 luxury villas under Elite Havens. In Europe, the company operates the upper-upscale Dusit Suites Athens in Greece, located in the vibrant coastal district of Glyfada on the Athenian #dusitinternational The issuer is solely responsible for the content of this announcement.


Free Malaysia Today
2 days ago
- Free Malaysia Today
Pharma shares slump after Trump price threat
Donald Trump is targeting cutting US drug prices, which are among the world's highest. (AFP pic) PARIS : Shares in European pharmaceutical firms slumped on Friday following a threat by president Donald Trump to punish them if they don't lower prices for medicines in the US. Shares in Novo Nordisk, the Danish maker of the blockbuster diabetes and weight-loss treatments Ozempic and Wegovy, saw shares drop 4.5% shortly after trading got under way in Copenhagen. Shares in Britain's AstraZeneca fell 2.8% in London, while Sanofi fell 1.1% in Paris. Meanwhile shares in Novartis shed 0.9% and Roche 1.0% after Trump announced Swiss goods will face a 39% tariff starting next week. Trump told major pharmaceutical firms Thursday to lower prices or face punishment, as he moved to give Americans relief from medicine costs much higher than elsewhere in the world. In letters to 17 drug companies published on his platform Truth Social, Trump said he wants the firms to work with his administration to institute a series of changes within 60 days. 'If you refuse to step up we will deploy every tool in our arsenal to protect American families from continued abusive drug pricing practices,' Trump wrote without specifying what the consequences would entail. Trump is following up on an executive order he signed in May to address US drug prices that are among the highest in the world – more than three times what people in similarly developed countries pay, the White House said Thursday.