
Scientists discover speech habit that could indicate Alzheimer's
Around 90,000 people in Scotland live with dementia, and it is estimated that two thirds of these cases are Alzheimer's. But while the condition has a range of signs, notably a decline in memory, a new study has discovered a certain speech trait that could foreshadow the degenerative disease.
The study, conducted by the University of Toronto, discovered that how fast someone speaks, and how hesitant they are in their choice of words can serve as an indicator for Alzheimer's. Lethologica, which is the inability to think of a certain word, is associated with cognitive decline, and the scientists aimed to analyse this phenomenon further.
The researchers asked 125 healthy adults between the ages of 18 and 90 to describe a scene in detail. They were shown pictures of everyday objects while listening to audio that aimed to either confuse them or help them identify the objects in the image.
One example of this from the study is that if participants were shown a picture of a broom, the audio could say 'groom', which helps them to remember the rhyming word.
But the less helpful audio could also offer a related word like 'mop', which can temporarily confuse the brain of the participant.
It was found that those who spoke faster in the initial easier task faired better and were faster at the second more difficult task.
And as predicted, older patients were slower and showed more signs of cognitive decline than younger participants.
"It is clear that older adults are significantly slower than younger adults in completing various cognitive tasks, including word-production tasks such as picture naming, answering questions, or reading written words," explained a team led by University of Toronto psychologist Hsi T. Wei.
"In natural speech, older adults also tend to produce more dysfluencies such as unfilled and filled pauses (e.g., "uh" and "um") in between speech and have a generally slower speech rate."
This slowing down of the brain is known as 'processing speed theory', and is central to conditions associated with cognitive decline, such as Alzheimer's.
The findings support the theory that a decrease in memory is not the only sign of cognitive decline, but that the overall processing speed of the brain slows down with conditions such as Alzheimer's and dementia.
Science Alert reports that some AI algorithms have even been able to predict Alzheimer's with an accuracy of 78.5 percent using speech patterns of patients alone.
And this is not the first study to focus on the link between speech and Alzheimer's.
Previous research has shown that people who have more signs of amyloid plaque in their brains, which is a textbook mark of Alzheimer's, are 1.2 times more likely to experience problems with their speech.
A study by Stanford University last year also found that longer pauses and slower speech rates were associated with higher levels of tangled tau proteins, which is another classic sign of Alzheimer's.
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Daily Record
a day ago
- Daily Record
Scientists discover speech habit that could indicate Alzheimer's
Certain ways of speaking can indicate cognitive decline, according to research. Around 90,000 people in Scotland live with dementia, and it is estimated that two thirds of these cases are Alzheimer's. But while the condition has a range of signs, notably a decline in memory, a new study has discovered a certain speech trait that could foreshadow the degenerative disease. The study, conducted by the University of Toronto, discovered that how fast someone speaks, and how hesitant they are in their choice of words can serve as an indicator for Alzheimer's. Lethologica, which is the inability to think of a certain word, is associated with cognitive decline, and the scientists aimed to analyse this phenomenon further. The researchers asked 125 healthy adults between the ages of 18 and 90 to describe a scene in detail. They were shown pictures of everyday objects while listening to audio that aimed to either confuse them or help them identify the objects in the image. One example of this from the study is that if participants were shown a picture of a broom, the audio could say 'groom', which helps them to remember the rhyming word. But the less helpful audio could also offer a related word like 'mop', which can temporarily confuse the brain of the participant. It was found that those who spoke faster in the initial easier task faired better and were faster at the second more difficult task. And as predicted, older patients were slower and showed more signs of cognitive decline than younger participants. "It is clear that older adults are significantly slower than younger adults in completing various cognitive tasks, including word-production tasks such as picture naming, answering questions, or reading written words," explained a team led by University of Toronto psychologist Hsi T. Wei. "In natural speech, older adults also tend to produce more dysfluencies such as unfilled and filled pauses (e.g., "uh" and "um") in between speech and have a generally slower speech rate." This slowing down of the brain is known as 'processing speed theory', and is central to conditions associated with cognitive decline, such as Alzheimer's. The findings support the theory that a decrease in memory is not the only sign of cognitive decline, but that the overall processing speed of the brain slows down with conditions such as Alzheimer's and dementia. Science Alert reports that some AI algorithms have even been able to predict Alzheimer's with an accuracy of 78.5 percent using speech patterns of patients alone. And this is not the first study to focus on the link between speech and Alzheimer's. Previous research has shown that people who have more signs of amyloid plaque in their brains, which is a textbook mark of Alzheimer's, are 1.2 times more likely to experience problems with their speech. A study by Stanford University last year also found that longer pauses and slower speech rates were associated with higher levels of tangled tau proteins, which is another classic sign of Alzheimer's. Join the Daily Record WhatsApp community! Get the latest news sent straight to your messages by joining our WhatsApp community today. You'll receive daily updates on breaking news as well as the top headlines across Scotland. No one will be able to see who is signed up and no one can send messages except the Daily Record team. All you have to do is click here if you're on mobile, select 'Join Community' and you're in! If you're on a desktop, simply scan the QR code above with your phone and click 'Join Community'. We also treat our community members to special offers, promotions, and adverts from us and our partners. If you don't like our community, you can check out any time you like. To leave our community click on the name at the top of your screen and choose 'exit group'.


Daily Mirror
a day ago
- Daily Mirror
'The heartbreaking day my wife Fiona Phillips didn't recognise our own son'
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Scottish Sun
a day ago
- Scottish Sun
Two common infections may trigger Alzheimer's, scientists warn – are you at risk?
Click to share on X/Twitter (Opens in new window) Click to share on Facebook (Opens in new window) SCIENTISTS have spent decades trying to understand what causes dementia. Is it alcohol? Obesity? Or are some of us simply genetically predisposed? Sign up for Scottish Sun newsletter Sign up 1 Two common infections may play a role in the development of Alzheimer's Credit: Getty The evidence is mixed - though experts generally agree that there are several factors involved in the abnormal build-up of proteins called amyloid and tau, which are what cause symptoms. A new review by Philadelphia College of Osteopathic Medicine, Pennsylvania, suggests two common infections may play a role. Researchers found both chlamydia pneumoniae and SARS-CoV-2 increase the levels of substances in the brain called cytokines. These trigger inflammation, which can "harm brain cells and may help speed up the buildup of harmful proteins linked to Alzheimer's". Chlamydia pneumoniae is a "very common" type of bacteria that causes lung infections, including pneumonia. It affects about 50 per cent of people by age 20, and 75 per cent by 65, and is passed on by sneezing and coughing, according to Superdrug. It is not the same as the STI chlamydia, though both are highly infectious. SARS-CoV-2 is the virus that causes Covid-19. In 2022, seven in 10 people in England were thought to have been infected. That number is now likely much higher. The report, published in Frontiers in Aging Neuroscience, found chlamydia pneumoniae and SARS-CoV-2 can invade the central nervous system through the blood-brain barrier and, "potentially more importantly", the olfactory route, which is responsible for our sense of smell. Common painkiller used for back pain ups risk of dementia by 29%, scientists warn "The olfactory system is lined with a specialised tissue called neuroepithelium that can serve as an entry point for pathogens to the brain," the authors said. "After initial infection, these microbes can travel along the olfactory nerves, ultimately reaching the brain's olfactory bulbs, which are linked to areas of the brain for memory and cognition. "This pathway is particularly relevant given that loss of smell is an early symptom in both Covid-19 and Alzheimer's disease." We hope to create new avenues for prevention and treatment Dr Brian J Balin They looked at patients with certain genetic factors known to significantly increase a person's risk of developing Alzheimer's - the most common form of dementia. This included APOE - a protein which transports fatty molecules like cholesterol to cells in our brain. Everyone carries two copies of APOE, one inherited from each parent. The three most common variants are APOE2, APOE3 and APOE4. Having at least one APOE4 variant is said to double or triple the risk of developing Alzheimer's, and someone with two variants is eight to 12 times more likely to get it, according to Alzheimer's Research UK. About one in 50 people carry two copies of APOE4. Scientists also examined the cytokines IL-6 and CCL2, which are involved in inflammation and immune responses in the body. Those carrying this gene variant appeared to be "more susceptible" to both chlamydia pneumoniae and SARS-CoV-2, "potentially amplifying" their risk for developing Alzheimer's. Co-author Dr Brian J Balin, a professor of neuroscience and neuropathology and director of the Center for Chronic Disorders of Aging, said: "These findings bring us one step closer to understanding the complex interactions between infections and Alzheimer's disease. "As we continue to learn more about the role infectious agents play in the development of this disease, we hope to create new avenues for prevention and treatment." 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Head injuries - people who have had a severe head injury may be at higher risk of developing Alzheimer's disease, but research is still needed in this area. Lifestyle factors and conditions - smoking, obesity, diabetes, high blood pressure are associated with a higher risk. Other factors - research suggests that hearing loss, untreated depression, loneliness or social isolation and a sedentary lifestyle may also play a role. About 980,000 people in the UK are living with dementia. This number is expected to rise to more than 1.4million by 2040. Alzheimer's is the most common form of dementia, accounting for between 60 and 80 per cent of all cases. Symptoms often develop slowly over several years and they may not be obvious at first. In the early stages, it can be difficult to tell the difference between memory problems caused by Alzheimer's, and mild forgetfulness that happens as we get older. But memory loss is one of the most common early symptoms, and may include losing memories of recent events, asking the same questions repeatedly, or having difficulty following conversation and learning new information. Patients may go on to regularly forget names and faces, repeat the same behaviours and routines, regularly misplace things, become confused about the date or time of day, feel disorientated in unfamiliar places, have problems finding the right words, or become low in mood, anxious or agitated. As Alzheimer's progresses, it can impact other areas of life, including communication, sleep, movement, senses and day-to-day care. If you are worried that you or a loved one are experiencing symptoms of Alzheimer's, speak to your GP. While there is no cure, there are treatment options to help manage your symptoms for a time.