GWS star Callaghan out for a month, TDK return looms
But Carlton star Tom De Koning (larynx) headlines four returning Blues for the Giants clash at Marvel Stadium.
Callaghan was hurt in a collision with Fremantle's Patrick Voss on the three-quarter time siren in the Giants' home defeat.
The 22-year-old ball-winner has avoided surgery, but could still spend six weeks on the sidelines.
Coniglio's return to play from a glute complaint has been pushed back again to four weeks after being listed as a test against Fremantle.
The 31-year-old midfielder will meet with a specialist after struggling to meet his training re-load demands.
He has been sidelined since round four and was originally slated to miss just one week.
Fellow Giants midfielder Toby McMullin also suffered an injury against the Dockers, but is expected to miss only one week with adductor irritation.
De Koning, meanwhile, is likely to return alongside Blake Acres (shoulder), Lachie Fogarty (hamstring) and Orazio Fantasia (calf) for the Blues.
Elsewhere, Collingwood captain Darcy Moore (shoulder) and fellow defender Dan Houston (calf) will have to prove their fitness later in the week.
Dion Prestia (achilles) will be available to play in Richmond's Dreamtime clash against Essendon, while the Bombers are primed to welcome back forward Jade Gresham (adductor).
Bombers midfielder Darcy Parish is set to make his return from a calf complaint via the VFL.
Brisbane are tossing up resting ruck Oscar McInerney again, while midfielder Jarrod Berry will be a chance to line up against Hawthorn after recovering from a concussion.
McInerney (soreness) was a late out from their eventual loss to Melbourne.
The Lions are hopeful defender Brandon Starcevich will make his return from a concussion within three to five weeks.
Starcevich suffered the concussion in round one and will move into full training over the next weeks.
Gold Coast forward Elliot Himmelberg's season is over after he ruptured his anterior cruciate ligament in the VFL.
He was one of three casualties from the reserves match, joined by ruck Max Knobel (foot) and forward Lloyd Johnston (concussion).
North Melbourne defender Darcy Tucker has also suffered a season-ending injury and will require back surgery.
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