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Malnutrition, not sugar: the surprising truth about type 5 diabetes
Malnutrition, not sugar: the surprising truth about type 5 diabetes

IOL News

time08-07-2025

  • Health
  • IOL News

Malnutrition, not sugar: the surprising truth about type 5 diabetes

Whether it's rooted in excess or scarcity, diabetes is a growing global crisis. Image: Polina Tankilevitch /pexels Type 5 Diabetes is real - and it's tied to malnutrition, not sugar. Here's what you need to know: For years, diabetes has been framed as a lifestyle condition linked to poor diet and weight gain, but that's not the full story. A new type of diabetes, now officially recognised by the International Diabetes Federation (IDF) as Type 5 diabetes, is turning that belief on its head. And it's hitting the world's poorest communities hardest. On April 9, Type 5 diabetes was formally added to the global classification system, the first new entry of its kind in decades. What makes this type different? It's caused not by overnutrition, but by chronic undernutrition and the people most at risk aren't those with excess fat, but those without enough food during critical early stages of development. 'Malnutrition‑related diabetes has historically been vastly under‑diagnosed and poorly understood,' said Dr Meredith Hawkins, endocrinologist at Albert Einstein College of Medicine and founding director of the Global Diabetes Institute (GDI), in an interview with Video Player is loading. Play Video Play Unmute Current Time 0:00 / Duration -:- Loaded : 0% Stream Type LIVE Seek to live, currently behind live LIVE Remaining Time - 0:00 This is a modal window. Beginning of dialog window. Escape will cancel and close the window. Text Color White Black Red Green Blue Yellow Magenta Cyan Transparency Opaque Semi-Transparent Background Color Black White Red Green Blue Yellow Magenta Cyan Transparency Opaque Semi-Transparent Transparent Window Color Black White Red Green Blue Yellow Magenta Cyan Transparency Transparent Semi-Transparent Opaque Font Size 50% 75% 100% 125% 150% 175% 200% 300% 400% Text Edge Style None Raised Depressed Uniform Dropshadow Font Family Proportional Sans-Serif Monospace Sans-Serif Proportional Serif Monospace Serif Casual Script Small Caps Reset restore all settings to the default values Done Close Modal Dialog End of dialog window. Advertisement Next Stay Close ✕ Type 5 diabetes is caused by malnutrition during early development, not overeating common in lean people. Image: Lagos Food Bank Initiative/pexels What is Type 5 diabetes? Type 5 diabetes primarily affects people in Asia and Africa, especially lean adolescents and young adults who experienced poor nutrition during childhood. According to the IDF Diabetes Atlas (11th edition), about 20 to 25 million people are already living with this type a number that rivals HIV infection rates in the same regions. Unlike the familiar Type 2 diabetes, which is often linked to high-calorie diets and obesity, Type 5 develops when the pancreas fails to develop fully in childhood due to nutrient deficiencies particularly low protein intake during pregnancy or adolescence. An article cited in "The Conversation" explains that rodent models have shown a clear connection between a low-protein diet and underdeveloped pancreases, which translates to reduced insulin production capacity. Simply put: if your body never built enough insulin-producing cells as a child, you're at higher risk for developing diabetes later even if you stay lean and active. This newly recognised condition is more than a medical milestone it's a call to rethink global health narratives. Most public awareness campaigns around diabetes centre on obesity, sugar, and sedentary lifestyles, often overlooking the fact that millions of people face a very different risk one rooted in poverty and food insecurity. This also exposes the health gap in countries battling undernutrition and limited access to healthcare. Type 5 diabetes often goes undiagnosed or misdiagnosed, as it doesn't fit the typical profile healthcare workers are trained to look for. As Hawkins noted, expanding our understanding of diabetes types is not just about labels; it's about making sure the right people get the right treatment. Recognising Type 5 diabetes is just the beginning. Image: Nataliya Vaitkevich/pexels Types of diabetes Here's a simplified breakdown of the major types of diabetes to better understand where Type 5 fits in: Type 1 Diabetes: An autoimmune condition where the body attacks insulin-producing cells. Usually appears early in life. Not linked to diet or weight. Treated with lifelong insulin therapy Type 2 Diabetes: The most common type, often linked to obesity but not exclusively This can be reversed with diet, exercise, and medication (like Metformin) Ethnic background and genetics also play a role Managed through lifestyle changes, tablets or insulin Gestational Diabetes Temporary condition during pregnancy due to hormonal shifts. Increases the future risk of Type 2 diabetes. Treated with dietary changes, insulin or tablets. Type 5 Diabetes Caused by malnutrition during early development, not overeating. Common in lean people, especially in resource-poor countries. Requires a new clinical approach to diagnosis and treatment. Still under-recognised in mainstream health systems. Why nutritional equity is keyType 5 diabetes shines a spotlight on how early-life nutrition or the lack thereof can leave permanent damage. It also challenges the global focus on obesity as the face of diabetes, urging health systems to prioritise food security and maternal nutrition as long-term investments in public health. This is more than a medical discovery, it's a wake-up call. With nearly one in nine adults living with diabetes worldwide, and more than 250 million people undiagnosed (International Diabetes Federation, IDF), it's time to think of diabetes in a new light, one that looks at inequality, not just indulgence. Whether it's rooted in excess or scarcity, diabetes is a growing global crisis. Recognising Type 5 diabetes is just the beginning. Now, the challenge is making sure people in affected communities are seen, heard, and treated starting with redefining the narrative around who is at risk and why.

Vascarta Receives FDA Orphan Drug Designation for Vasceptor® in the Treatment of Sickle Cell Disease
Vascarta Receives FDA Orphan Drug Designation for Vasceptor® in the Treatment of Sickle Cell Disease

Malaysian Reserve

time12-06-2025

  • Business
  • Malaysian Reserve

Vascarta Receives FDA Orphan Drug Designation for Vasceptor® in the Treatment of Sickle Cell Disease

SUMMIT, N.J., June 12, 2025 /PRNewswire/ — Vascarta Inc., a biopharmaceutical company committed to advancing innovative therapies for underserved patient populations, announced today that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation to its lead drug candidate, Vasceptor® (VAS-101), for the treatment of Sickle Cell Disease (SCD). Orphan Drug Designation is awarded to therapies intended to treat rare diseases that affect fewer than 200,000 people in the United States. This designation provides significant benefits, including seven years of market exclusivity upon approval, tax credits for qualified clinical trials, and exemption from certain FDA fees. 'The attainment of Orphan Drug Designation represents an important regulatory milestone for Vascarta and underscores the therapeutic potential of Vasceptor® to provide safe and effective relief to patients living with this debilitating disease,' said Dr. Richard Prince, CEO & President of Vascarta. 'We plan to work closely with the United States Food & Drug Administration to bring Vasceptor® to market as rapidly as possible.' Dr. Joel Friedman, Professor, Department of Microbiology & Immunology, Albert Einstein College of Medicine, and Vascarta Scientific Founder & Head, Scientific Advisory Board, stated, 'The preclinical results to date showing pain reduction and therapeutic efficacy resulting from our novel approach of targeting red blood cell instability, neuro-inflammation and vascular inflammation bodes well for the development of a widely accessible therapy that prevents and treats many if not most of the clinical consequences of SCD.' Vasceptor® is exclusively licensed to Vascarta from the Albert Einstein College of Medicine (Bronx, New York, USA). About Vasceptor® (VAS-101) VAS-101, developed by Vascarta Inc. (Summit, NJ, USA), is a patented topical curcumin formulation that is delivered using patented transdermal technology and that is designed to overcome the limited bioavailability and suboptimal effectiveness of oral dosing of curcumin. A study in PNAS Nexus suggests VAS-101 may reduce chronic pain, stabilize red blood cells, and lower inflammation in sickle cell disease (SCD). It is currently in a Phase 1 clinical trial at the Foundation for Sickle Cell Disease Research (FSCDR) in Hollywood, Florida. While curcumin is known for its safety and anti-inflammatory, antioxidant, and anti-sickling properties, its clinical use has been limited by poor oral bioavailability. About Sickle Cell Disease Sickle Cell Disease is the most common inherited genetic disorder that affects primarily African American and non – Hispanic Black individuals in the United States. SCD associated complications include anemia, acute and chronic pain, infections, pneumonia and acute chest syndrome, stroke, kidney, liver, and heart disease. Current estimates indicate there are 175,000 cases of SCD in the USA and 45,000 in European Union countries. The estimated life expectancy of those with sickle cell disease in the USA is more than 20 years shorter than the average expected lifespan. SCD is caused by a single point mutation in the globin gene leading to sickling of red blood cells. It is characterized by severe pain, inflammation, oxidative stress, and organ damage, which contributes to the poor quality of life and reduced survival. Recently approved SCD therapies do not mitigate pain, and patients are often on multiple drugs which often have undesirable side effects. The unmet medical need for most SCD sufferers is significant. Better therapies that are safe, improve outcomes, optimize compliance for patients of all ages, minimize the need for blood transfusions, and reduce the need for chronic administration of potentially harmful pain medications are needed. About Vascarta Vascarta Inc. is a clinical stage pharmaceutical company developing efficient transdermal and transmucosal delivery of pharmaceuticals to address inflammatory conditions with an initial focus on Sickle Cell Disease and osteoarthritis. To learn more, contact Vascarta Chairman, CEO & President, Dr. Richard Prince, at rprince@ Media requests should be directed to David Hymson at dhymson@

Axsome Therapeutics Showcases Innovation in Sleep Medicine with Multiple Presentations for AXS-12 and Solriamfetol at SLEEP 2025
Axsome Therapeutics Showcases Innovation in Sleep Medicine with Multiple Presentations for AXS-12 and Solriamfetol at SLEEP 2025

Hamilton Spectator

time11-06-2025

  • Health
  • Hamilton Spectator

Axsome Therapeutics Showcases Innovation in Sleep Medicine with Multiple Presentations for AXS-12 and Solriamfetol at SLEEP 2025

NEW YORK, June 11, 2025 (GLOBE NEWSWIRE) — Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders, today announced seven presentations, including two featured oral plenary sessions, on AXS-12 and solriamfetol, at SLEEP 2025, the 39th annual meeting of the Associated Professional Sleep Societies (APSS), being held June 8-11, 2025, in Seattle, Washington. Details for the presentations are as follows: AXS-12 Title: ENCORE: Topline Results of a Phase 3 Open-Label Extension and Randomized-Withdrawal Trial of AXS-12 in Narcolepsy Lead Author: Richard Bogan, MD, FCCP, FAASM, Associate Clinical Professor at the University of South Carolina School of Medicine in Columbia, SC Poster Presentation Date and Time: Wednesday, June 11, 10 - 11:45 a.m. PT Poster Session: P-51 Poster Number: 405 Title: Impact of AXS-12 on Symptom Severity and Functional Impairment in Narcolepsy: Results from the Phase 3 SYMPHONY Trial Lead Author: Michael Thorpy, MD, Director of the Sleep-Wake Disorders Center at the Montefiore Medical Center and Professor of Neurology at Albert Einstein College of Medicine, New York, NY Oral Presentation Date and Time: Wednesday, June 11, 3:45 - 4 p.m. PT Oral Session: O-24 Poster Presentation Date and Time: Wednesday, June 11, 10 - 11:45 a.m. PT Poster Session: P-51 Poster Number: 390 Title: Residual Symptom Burden in Patients with Narcolepsy Satisfied with Treatment: Subgroup Analysis from the CRESCENDO Survey Lead Author: Michael Thorpy, MD, Director of the Sleep-Wake Disorders Center at the Montefiore Medical Center and Professor of Neurology at Albert Einstein College of Medicine, New York, NY Oral Presentation Date and Time: Wednesday, June 11, 4 - 4:15 p.m. PT Oral Session: O-24 Poster Presentation Date and Time: Wednesday, June 11, 10 - 11:45 a.m. PT Poster Session: P-51 Poster Number: 391 Solriamfetol Title: Effects of Solriamfetol on Neuropsychological Outcomes in Patients with Obstructive Sleep Apnea in the Real-World SURWEY Study Lead Author: Yaroslav Winter, MD, Mainz Comprehensive Epilepsy and Sleep Medicine Center, Department of Neurology, Johannes Gutenberg-University, Mainz, Germany Poster Presentation Date and Time: Wednesday, June 11, 10 - 11:45 a.m. PT Poster Session: P-50 Poster Number: 366 Title: Real-World Use of Solriamfetol for Excessive Daytime Sleepiness in Patients with Obstructive Sleep Apnea in the US Lead Author: Yang Zhao, PhD, Axsome Therapeutics Poster Presentation Date and Time: Wednesday, June 11, 10 - 11:45 a.m. PT Poster Session: P-50 Poster Number: 369 About AXS-12 AXS-12 (reboxetine) is a highly selective and potent norepinephrine reuptake inhibitor and cortical dopamine modulator under development for the treatment of narcolepsy. AXS-12 is thought to modulate noradrenergic activity to promote maintain tone during wakefulness, and noradrenergic and cortical dopamine signaling to promote wakefulness and enhance cognition. AXS-12 has been granted U.S. Food and Drug Administration (FDA) Orphan Drug Designation for the treatment of narcolepsy. AXS-12 is covered by issued patents providing protection to at least 2039. AXS-12 is an investigational drug product not approved by the FDA. About Solriamfetol Solriamfetol is a dopamine and norepinephrine reuptake inhibitor (DNRI), TAAR1 agonist, and 5-HT1A agonist being developed for the treatment of attention deficit hyperactivity disorder (ADHD), major depressive disorder (MDD), binge eating disorder (BED), and excessive sleepiness associated with shift work disorder (SWD). About Axsome Therapeutics Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain's biggest problems so patients and their loved ones can flourish. For more information, please visit us at and follow us on LinkedIn and X . Forward Looking Statements Certain matters discussed in this press release are 'forward-looking statements'. The Company may, in some cases, use terms such as 'predicts,' 'believes,' 'potential,' 'continue,' 'estimates,' 'anticipates,' 'expects,' 'plans,' 'intends,' 'may,' 'could,' 'might,' 'will,' 'should' or other words that convey uncertainty of future events or outcomes to identify these forward-looking statements. In particular, the Company's statements regarding trends and potential future results are examples of such forward-looking statements. The forward-looking statements include risks and uncertainties, including, but not limited to, the commercial success of the Company's SUNOSI®, AUVELITY®, and SYMBRAVO® products and the success of the Company's efforts to obtain any additional indication(s) with respect to solriamfetol and/or AXS-05; the Company's ability to maintain and expand payer coverage; the success, timing and cost of the Company's ongoing clinical trials and anticipated clinical trials for the Company's current product candidates, including statements regarding the timing of initiation, pace of enrollment and completion of the trials (including the Company's ability to fully fund the Company's disclosed clinical trials, which assumes no material changes to the Company's currently projected revenues or expenses), futility analyses and receipt of interim results, which are not necessarily indicative of the final results of the Company's ongoing clinical trials, and/or data readouts, and the number or type of studies or nature of results necessary to support the filing of a new drug application ('NDA') for any of the Company's current product candidates; the Company's ability to fund additional clinical trials to continue the advancement of the Company's product candidates; the timing of and the Company's ability to obtain and maintain U.S. Food and Drug Administration ('FDA') or other regulatory authority approval of, or other action with respect to, the Company's product candidates, including statements regarding the timing of any NDA submission; the Company's ability to successfully defend its intellectual property or obtain the necessary licenses at a cost acceptable to the Company, if at all; the Company's ability to successfully resolve any intellectual property litigation, and even if such disputes are settled, whether the applicable federal agencies will approve of such settlements; the successful implementation of the Company's research and development programs and collaborations; the success of the Company's license agreements; the acceptance by the market of the Company's products and product candidates, if approved; the Company's anticipated capital requirements, including the amount of capital required for the commercialization of SUNOSI, AUVELITY, and SYMBRAVO and for the Company's commercial launch of its other product candidates, if approved, and the potential impact on the Company's anticipated cash runway; the Company's ability to convert sales to recognized revenue and maintain a favorable gross to net sales; unforeseen circumstances or other disruptions to normal business operations arising from or related to domestic political climate, geo-political conflicts or a global pandemic and other factors, including general economic conditions and regulatory developments, not within the Company's control. The factors discussed herein could cause actual results and developments to be materially different from those expressed in or implied by such statements. The forward-looking statements are made only as of the date of this press release and the Company undertakes no obligation to publicly update such forward-looking statements to reflect subsequent events or circumstances. Investors: Mark Jacobson Chief Operating Officer (212) 332-3243 mjacobson@ Media: Darren Opland Director, Corporate Communications (929) 837-1065 dopland@

Bobbi Brown, Lauren Bush Lauren and More Honored at Einstein College of Medicine Spirit of Achievement Luncheon
Bobbi Brown, Lauren Bush Lauren and More Honored at Einstein College of Medicine Spirit of Achievement Luncheon

Yahoo

time16-05-2025

  • Entertainment
  • Yahoo

Bobbi Brown, Lauren Bush Lauren and More Honored at Einstein College of Medicine Spirit of Achievement Luncheon

On Tuesday, the Albert Einstein College of Medicine's Women's Division hosted its annual Spirit of Achievement luncheon honoring makeup artist and Jones Road Beauty founder Bobbi Brown (trailblazer award honoree); founder and chief executive officer of lifestyle brand committed to solving world hunger Feed Lauren Bush Lauren (visionary award honoree), chair and professor at Albert Einstein College of Medicine Teresa Bowman Ph.D. (Ruth L. Gottesman award for scientific advancement honoree) and philanthropist and member of board of trustees at Albert Einstein College of Medicine Linda Altman (leadership award honoree). The event, held at the Rainbow Room in New York, is the longest running benefit luncheon in the city. Prior to the lunch, honorees and attendees mingled over mimosas and posed for the step-and-repeat. More from WWD Skin Care Pioneer Ole Henriksen Announces 'The Glowing Man' Biopic in Cannes All the Beauty Retail Expansions of 2025 Twelve Years After Hitting the Market, Men's Grooming Brand Harry's Is Launching a New Razor Both Brown and Bush Lauren were humbled to be honored with an award from an institution centered around science for their work in beauty and world hunger, respectively. 'I'm honored to share this award with some of my role models, from Eleanor Roosevelt to Gloria Steinem to Meryl Streep,' Brown said during her speech. 'I'm just a nice Jewish girl from Chicago who decided to become a makeup artist. How? Why am I in this room? I'm not sure.' Brown also joked that she hopes 'to tell all the other creative kids that don't get good grades in math and science, there is hope….I'm very honored, especially for someone that got Ds in science to get this science award. It's pretty amazing, but it's really about all the amazing doctors and women that make a big difference.' Ahead of the event, Bush Lauren said: 'I'm very honored to be honored with Bobbi, who's an old friend of mine, and just from an amazing organization doing really important research and clinical care. It's a little surreal, to be honest.' Like Brown, Bush Lauren was humbled by the array of past honorees, which also include Donna Karan, Diane von Furstenberg, Evelyn Lauder and Iris Apfel. Bush Lauren added: '[It's] an honor in itself to be considered amongst those women. For me, I've just been held up and lifted up by so many women, obviously my mom, my family, my sister, my girlfriends and fellow female entrepreneurs have like been my little tribe during the last 20 years of building Feed. Without them and that support Feed certainly would not be here.' While Brown and Bush Lauren were honored for their successes, the focus throughout the event was on the scientific advancements coming out of the college, including Bowman's research on blood stem cells via zebrafish, which respond similarly to humans. Best of WWD The Best Makeup Looks in Golden Globes History A Look Back at Golden Globes Best Makeup on the Red Carpet, From Megan Fox to Sophia Loren [PHOTOS] The Best Hairstyles in Golden Globes History

Robert De Niro Hits the Cannes Red Carpet with Partner Tiffany Chen, Plus Eva Longoria, Selena Gomez and More
Robert De Niro Hits the Cannes Red Carpet with Partner Tiffany Chen, Plus Eva Longoria, Selena Gomez and More

Yahoo

time14-05-2025

  • Entertainment
  • Yahoo

Robert De Niro Hits the Cannes Red Carpet with Partner Tiffany Chen, Plus Eva Longoria, Selena Gomez and More

Stars have been everywhere this week. At the Cannes Film Festival, Robert De Niro steps out for a rare appearance with his partner, Tiffany Chen, while Eva Longoria dazzles fans upon arrival. In New York, Only Murders in the Building costars Martin Short, Selena Gomez and Steve Martin promote their show while Nick Jonas is out and about. Here are the best photos of celebs out and about this week. Come back tomorrow for more of the latest A-list outings! Robert De Niro and his partner Tiffany Chen arrive in style on the red carpet at the Cannes Film Festival in France on May 13. Martin Short, Selena Gomez and Steve Martin celebrate the upcoming fifth season of Only Murders in the Building at Disney Upfront in New York City on May 13. Eva Longoria is all smiles on the red carpet at the Cannes Film Festival in France on May 13. Nick Jonas looks cool as ever as he takes a stroll around New York City on May 13. Bella Hadid waves to the crowd at the Cannes Film Festival in France on May 13. Quentin Tarantino embraces his wife Daniella at the Cannes Film Festival in France on May 13. Pete Davidson steps out with girlfriend Elsie Hewitt in New York City on May 13. Jason Weinberg, Demi Moore and Merritt Johnson attend Family Equality's Night at the Pier event to raise money for LGBTQ+ families in New York City on May 12. Chandra Wilson reps Grey's Anatomy at Disney Upfront in New York City on May 13. Alfonso Ribeiro looks polished in purple while out in New York City on May 13. Bobbi Brown and Lauren Bush Lauren show their support at Albert Einstein College of Medicine's Spirit Awards in New York City on May 13. Heidi Klum looks radiant in a pink floral dress on her way to the Cannes Film Festival in France on May 13. Renée Zellweger gets sleuthing on the set of Only Murders in the Building in New York City on May 13. Timothée Chalamet and Kylie Jenner sit courtside at the playoff game between the Boston Celtics and the New York Knicks on May 12 in New York City. Travis and Jason Kelce host the Amazon Upfront, announcing the streamer's new projects, in New York City on May 12. Kate Middleton greets guests at the British Fashion Council in London on May 12, where she presents the Queen Elizabeth II Award for British Design. Amy Poehler and Tina Fey reunite at an NBCUniversal event announcing the network's primetime show lineup. Cardi B and NFL star Stefon Diggs fuel dating rumors as they celebrate the New York Knicks' win against the Boston Celtics on May 12 in New York City. Kelly Ripa, Nicole Scherzinger, and Mark Consuelos smile for a group shot while attending the Family Equality Gala on May 12 in New York City. Blake Shelton jams out at NBC's TODAY Citi Concert Series on May 13 in New York City. Justin Theroux walks the blue carpet at the Webby Awards in New York City on May 12. John Cena and wife Shay Shariatzadeh match in purple looks the Amazon Upfront on May 12 in New York City Dave Bautista and Jason Momoa make a grand arrival at the Amazon Upfront in New York City on May 12. Lizzo shows off her new blonde hair at the Amazon Upfront in New York City on May 12. Jurnee Smollett and Ciara celebrate the grand opening of Tory Burch's new flagship store on Rodeo Drive in Los Angeles on May 12. Pauline Chalamet, Kate Hudson and Jodie Turner-Smith look chic at the opening of Tory Burch's new flagship store in Los Angeles on May 12. Ryan Reynolds rocks a double-tan outfit on The Late Show with Stephen Colbert on May 12 in New York City. Maren Morris performs on The Tonight Show Starring Jimmy Fallon on May 12 in New York City Eva Longoria heads out of her hotel in Paris to the Cannes Film Festival on May 13. Robert De Niro and girlfriend Tiffany Chen arrive at the Cannes Film Festival in France on May 13. Halle Berry waves to fans at the Cannes Film Festival on May 13. Tom Brady shows off his famous football handling skills at the Fox Upfront in New York City on May 12. Elizabeth Hurley and Brendan Fraser smile at the Fox Upfront in New York City on May 12. Rob Lowe and Jon Hamm pose together at the Fox Upfront in New York City on May 12. Usher wears Emory University's robes as he gives their graduation commencement speech in Atlanta on May 12. Halle Berry radiates movie star energy as she enters Hotel Martinez in Paris ahead of the Cannes Film Festival on May 12. Tom Cruise dons a classic suit with a patterned tie as he prepares for the BFI Fellowship celebration for him in London on May 12. Days after hosting the ACM Awards, Reba McEntire flies to New York City for the NBCUniversal Upfront event on May 12. Snoop Dogg, in a bright blue tracksuit, carries a speaker as he enters Watch What Happens Live with Andy Cohen in New York City on May 12. Lizzo rocks full platinum blonde hair as she steps out in a black dress at Watch What Happens Live in New York City on May 12. Hannah Waddingham glows on the red carpet at the BFI Chair's Dinner in London on May 12. Bella Hadid goes blonde as she arrives at her hotel ahead of Cannes Film Festival in France on May 12. Gayle King and Nicole Scherzinger pop in vibrant colors at SiriusXM Studios in New York City on May 12. Heidi Klum and her husband Tom Kaulitz match in black at the Cannes Film Festival in France on May 12. Andrew Garfield and Monica Barbaro visit Isa Antonetti during a production of Buena Vista Social Club on Broadway in N.Y.C. on May 11. Kylie Jenner wears a pink bikini while enjoying the sun on the Turks and Caicos Islands on May 10. A shaded DJ Khaled holds up the MCM x Snipes collaboration at a launch party held at We The Best x Snipes in Miami. Ashley Madekwe, Shea McGee and Jamie Chung are ready for the spring at An Evening with Tuckerknuck and Studio McGee in West Hollywood, California, on May 8. Jordan Chiles tips her cowboy hat at an afterparty for Beyoncé's Cowboy Carter Tour in L.A. powered by SirDavis American Whisky, Marriott Bonvoy and EDITION on May 8. Terry Crews shows off his biceps in Spotify, FC Barcelona and Travis Scott's Cactus Jack merchandise in Barcelona on May 10. Walton Goggins delivers his opening monologue in his Saturday Night Live hosting debut in New York City on May 10. Gwen Stefani gets ready to take the stage at Wango Tango in Huntington Beach, California, wearing all denim on May 10. Jessie J, her son Sky, mom Rose Cornish and boyfriend Chanan Safir Colman have a family day at The Wiggles' tour stop in London on May 9. Abbott Elementary's William Stanford Davis stops by The Jennifer Hudson Show for a May 12 episode in Burbank, California. A casual Jennifer Lawrence totes a big yellow bag on a stroll in New York City on May 11. Daniel Dae Kim arrives at a closing night screening of Yellow Face in San Francisco on May 11. Michelle Williams' character is pregnant for A Place in Hell scene in New York City on May 11. Harry Hamlin holds an acting masterclass at the SAG-AFTRA Foundation in Los Angeles on May 11. Nicole Scherzinger wears a bright pink biker jacket to the opening night of The Last Bimbo of the Apocalypse in New York City on May 11. Benson Boone and his girlfriend Maggie Thurmon hold hands on a day around Malibu, California, on May 11. Host Alan Cumming looks dapper at the 2025 BAFTA TV Awards in London on May 11. Amber Rose reps the Houston Rockets at the Baddies Africa premiere in West Hollywood, California, on May 11. Megan Thee Stallion is a sheer beauty at the Gold Gala in Los Angeles on May 10. Also at the Gold Gala, H.E.R. sports a stylish pair of shades in Los Angeles on May 10. Meghan Trainor prepares to head onstage in a jewel-studded two-piece at Wango Tango in Huntington Beach, California, on May 10. Teddi Mellencamp arrives in white to Wango Tango in Huntington Beach, California, on May 10. A blonde Doja Cat strikes a pose on the Wango Tango red carpet in Huntington Beach, California, on May 10. Yvette Nicole Brown and her husband Anthony Davis are happy to be at the Spring Break Gala in Los Angeles on May 10. Dressed in a black dress, Michelle Monaghan steps out in the East Village in N.Y.C. on May 10. Timothée Chalamet cheers on the New York Knicks in game three against the Boston Celtics in N.Y.C. on May 10. Justin Theroux bundles up to attend the Poker Face pop-up with his dog Kuma in New York City on May 9. Saweetie celebrates Kali Uchis' new album Sincerely at a party in Hollywood, California, on May 9. Taraji P. Henson rocks an edgy look on The Jennifer Hudson Show for a May 9 episode in Burbank, California. Khloé Kardashian sparkles in sequins with an award at the German Perfume Award Duftstars in Dusseldorf, Germany, on May 8. Nicola Coughlan radiates old Hollywood glam at the 2025 BAFTA Television Awards in London on May 11. Tom Cruise speaks as a guest at the British Film Institute's Southbank location in London on May 11. Heidi Klum smiles for the cameras while walking through the Nice Côte d'Azur Airport ahead of the 2025 Cannes Film Festival in France on May 11. Chanel Iman and Victoria Monét celebrate a new Chasa collection at Porta Via in Beverly Hills, Calif., on May 9. Alan Cumming attends the 2025 BAFTA Television Awards in a dazzling blue blazer and leopard print in London on May 11. Viola Davis is joined by her daughter Genesis at the City Year Los Angeles' 14th annual Spring Break Gala held at SoFi Stadium in Inglewood, Calif., on May 9. Meghan Trainor makes a glamorous appearance in a pink bow outfit and pearl set at iHeartRadio's 102.7 KIIS FM Wango Tango in Huntington Beach, Calif., on May 10. Quinta Brunson smiles for the camera as she attends the City Year Los Angeles' Spring Break Gala in Inglewood, Calif., on May 9. Mariska Hargitay poses with her son August for a photo as they arrive at the Knicks playoff game at Madison Square Garden in New York City on May 10. Robert Irwin attends the Steve Irwin Gala held in honor of his late father to support the Wildlife Warriors conservationist organization at Las Vegas' Bellagio Resort & Casino on May 10. John Legend, Chrissy Teigen, Sandra Oh and Tan France put on their finest ensembles as they attend the Founders Party at the Gold House Gold Gala on May 10 in Los Angeles. Questlove, Fred Armisen, Dave Grohl and Judd Apatow attend the Ladies & Gentlemen...50 Years of SNL Music event at the Grammy Museum in Los Angeles on May 10. Amber Riley models a chic all-white look as she attends the Black Excellence Brunch by BET PLUS celebrating the Usher: Rendezvous in Paris concert film on May 10 in Los Angeles. Darren Barnet, Brenda Song, Ming-Na Wen, and Harry Shum Jr. pose for a photo as they attend the fourth annual Gold House Gold Gala on May 10 in Los Angeles. Colton Underwood speaks onstage at the third annual Hollywood & Mind Summit on May 9 in Los Angeles. Victoria Monét attends Mother's Day Party With a Purpose presented by the Elaine Welteroth and birthFUND in L.A. on May 10. Mariska Hargitay looks effortlessly cool outside Madison Square Garden in N.Y.C. on May 10. Tyra Banks strikes a pose while attending The Silver Party at The Hermitage in Sydney, Australia on May 10. Ben Stiller sits courtside during a match between the Boston Celtics and the New York Knicks at Madison Square Garden in New York City on May 10. Sophia Bush smiles wide at Mother's Day Party With a Purpose hosted by Elaine Welteroth and birthFUND in Los Angeles on May 10. John Krasinski, Sarah Snook and Matt Damon pose backstage at the Broadway play The Picture of Dorian Gray at The Music Box Theatre in New York City on May 9. Billie Eilish speaks on stage during the Billie Eilish and Support+Feed Present: OVERHEATED Berlin event at Festsaal Kreuzberg in Berlin on May 9. Sarah Paulson makes a fashion forward appearance at the Miu Miu Tales and Tellers event at New York City's Terminal Warehouse on May 9. Justin Hartley is dashing in a suit and shades as he is seen out in New York City on May 9. Hugh Jackman greets fans after performing with Ella Beatty in the off-Broadway play Sexual Misconduct of the Middle Classes on May 8 in New York City. Patti LaBelle takes to the stage on the opening night of The Queens! 4 Legends. 1 Stage Tour at the Michelob ULTRA Arena in Las Vegas on May 9. Shia LaBeouf attends the premiere and Q&A for his new film Henry Johnson in Santa Monica, Calif., on May 9. Chaka Khan gives a showstopping perfrormace onstage during the first night of The Queens! 4 Legends. 1 Stage Tour on May 9 in Las Vegas, Amy Grant lights up the stage as she performs at the Ryman Auditorium in Nashville on May 9. Jesse Metcalfe speaks onstage during day two of the Environmental Media Association IMPACT Summit 2025 presented By Toyota on May 9 in West Hollywood. Buffy the Vampire Slayer co-stars Alyson Hannigan and Sarah Michelle Gellar reunite at the Sirius XM studios in New York City on May 9. Gwyneth Paltrow unveils The Forest Within, an immersive recreation of a Korean forest, in New York City on May 9. Eva Longoria flashes a smile as she arrives at her hotel in Paris on May 9. Henry Golding grabs a quick bite at the Casting Directors' Luncheon in London on May 9. Lily Allen looks chic at the Casting Directors' luncheon in London on May 9. Nina Dobrev and fiancé Shaun White take a stroll through New York City with their dog on May 9. Natasha Lyonne looks gorgeous in a see-through dress after appearing on Late Night with Seth Meyers on May 9 in New York City. Jeff Timmons, Justin Jeffre, Nick Lachey and Drew Lachey of 98 Degrees make a stop at the Sirius XM Studios on May 9 in New York City. Tony Hawk hangs with pal Tony the Tiger at a celebration for his new video game, Tony Hawk's Pro Skater 3 + 4 in Los Angeles on May 8. Read the original article on People

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