Latest news with #JanJensen
Yahoo
6 days ago
- Business
- Yahoo
Trailhead Biosystems® Expands Human Cell-Based Product Line with iPSC-Derived A9 Dopaminergic Neurons
BEACHWOOD, Ohio, July 23, 2025 /PRNewswire/ -- Trailhead Biosystems, Inc. ( a biotechnology company pioneering the creation of induced pluripotent stem cell (iPSC)-derived human cells at scale for drug discovery and cell therapy, introduces TrailBio® A9 Dopaminergic Neurons, a powerful new tool available off-the-shelf for studying Parkinson's disease and other neurodegenerative conditions. A9 dopaminergic neurons play a critical role in movement regulation and are disproportionately affected in Parkinson's disease. Historically, researchers have lacked access to viable human models, relying instead on animal studies with limited relevance. With TrailBio® A9 Dopaminergic Neurons, scientists now have a human-specific platform to investigate disease mechanisms, develop therapies and accelerate drug discovery. "TrailBio® A9 Dopaminergic Neurons open new possibilities for Parkinson's research," said Dr. Jan Jensen, Chief Scientific Officer, Chief Technology Officer and founder of Trailhead Biosystems. "These cells enable researchers to study the vulnerabilities of A9 neurons, helping drive progress toward more effective treatments." "For decades, the lack of human A9 neurons has limited our ability to truly understand Parkinson's disease," added Dr. Nooshin Amini, Scientific Director at Trailhead Biosystems. "Now, with TrailBio® A9 Dopaminergic Neurons, researchers can directly study the exact cells that are most affected, offering hope for groundbreaking insights and future therapies." About Trailhead Biosystems Trailhead Biosystems, Inc. is pioneering an informatics-based approach in regenerative medicine and drug discovery. Founded in 2015 as a spinout from the Cleveland Clinic and Case Western Reserve University, Trailhead emerged from the research of CSO/CTO and founder Dr. Jan Jensen. Trailhead creates optimized human cells at scale with its proprietary High-Dimensional Design-of-Experiments (HD-DoE®) platform, integrating advanced mathematical modeling with high-throughput robotic manufacturing. This innovative system allows Trailhead to develop specialized, high-quality iPSC-derived human cells for drug discovery and cell-based therapies. TrailBio® A9 Dopaminergic Neurons represent one of many specialized human cell types emerging from this platform, with additional cell models expected in the near future. Learn more about Trailhead Biosystems, TrailBio® A9 Dopaminergic Neurons and HD-DoE® at For more information, please contact: Tim Mauk, Corporate CommunicationsTrailhead BiosystemsEmail: info@ View original content to download multimedia: SOURCE Trailhead Biosystems Inc Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
6 days ago
- Business
- Yahoo
Trailhead Biosystems® Expands Human Cell-Based Product Line with iPSC-Derived A9 Dopaminergic Neurons
BEACHWOOD, Ohio, July 23, 2025 /CNW/ -- Trailhead Biosystems, Inc. ( a biotechnology company pioneering the creation of induced pluripotent stem cell (iPSC)-derived human cells at scale for drug discovery and cell therapy, introduces TrailBio® A9 Dopaminergic Neurons, a powerful new tool available off-the-shelf for studying Parkinson's disease and other neurodegenerative conditions. A9 dopaminergic neurons play a critical role in movement regulation and are disproportionately affected in Parkinson's disease. Historically, researchers have lacked access to viable human models, relying instead on animal studies with limited relevance. With TrailBio® A9 Dopaminergic Neurons, scientists now have a human-specific platform to investigate disease mechanisms, develop therapies and accelerate drug discovery. "TrailBio® A9 Dopaminergic Neurons open new possibilities for Parkinson's research," said Dr. Jan Jensen, Chief Scientific Officer, Chief Technology Officer and founder of Trailhead Biosystems. "These cells enable researchers to study the vulnerabilities of A9 neurons, helping drive progress toward more effective treatments." "For decades, the lack of human A9 neurons has limited our ability to truly understand Parkinson's disease," added Dr. Nooshin Amini, Scientific Director at Trailhead Biosystems. "Now, with TrailBio® A9 Dopaminergic Neurons, researchers can directly study the exact cells that are most affected, offering hope for groundbreaking insights and future therapies." About Trailhead Biosystems Trailhead Biosystems, Inc. is pioneering an informatics-based approach in regenerative medicine and drug discovery. Founded in 2015 as a spinout from the Cleveland Clinic and Case Western Reserve University, Trailhead emerged from the research of CSO/CTO and founder Dr. Jan Jensen. Trailhead creates optimized human cells at scale with its proprietary High-Dimensional Design-of-Experiments (HD-DoE®) platform, integrating advanced mathematical modeling with high-throughput robotic manufacturing. This innovative system allows Trailhead to develop specialized, high-quality iPSC-derived human cells for drug discovery and cell-based therapies. TrailBio® A9 Dopaminergic Neurons represent one of many specialized human cell types emerging from this platform, with additional cell models expected in the near future. Learn more about Trailhead Biosystems, TrailBio® A9 Dopaminergic Neurons and HD-DoE® at For more information, please contact: Tim Mauk, Corporate CommunicationsTrailhead BiosystemsEmail: info@ View original content to download multimedia: SOURCE Trailhead Biosystems Inc View original content to download multimedia:
Cision Canada
6 days ago
- Business
- Cision Canada
Trailhead Biosystems® Expands Human Cell-Based Product Line with iPSC-Derived A9 Dopaminergic Neurons
BEACHWOOD, Ohio, July 23, 2025 /CNW/ -- Trailhead Biosystems, Inc. ( a biotechnology company pioneering the creation of induced pluripotent stem cell (iPSC)-derived human cells at scale for drug discovery and cell therapy, introduces TrailBio ® A9 Dopaminergic Neurons, a powerful new tool available off-the-shelf for studying Parkinson's disease and other neurodegenerative conditions. A9 dopaminergic neurons play a critical role in movement regulation and are disproportionately affected in Parkinson's disease. Historically, researchers have lacked access to viable human models, relying instead on animal studies with limited relevance. With TrailBio ® A9 Dopaminergic Neurons, scientists now have a human-specific platform to investigate disease mechanisms, develop therapies and accelerate drug discovery. "TrailBio ® A9 Dopaminergic Neurons open new possibilities for Parkinson's research," said Dr. Jan Jensen, Chief Scientific Officer, Chief Technology Officer and founder of Trailhead Biosystems. "These cells enable researchers to study the vulnerabilities of A9 neurons, helping drive progress toward more effective treatments." "For decades, the lack of human A9 neurons has limited our ability to truly understand Parkinson's disease," added Dr. Nooshin Amini, Scientific Director at Trailhead Biosystems. "Now, with TrailBio ® A9 Dopaminergic Neurons, researchers can directly study the exact cells that are most affected, offering hope for groundbreaking insights and future therapies." About Trailhead Biosystems Trailhead Biosystems, Inc. is pioneering an informatics-based approach in regenerative medicine and drug discovery. Founded in 2015 as a spinout from the Cleveland Clinic and Case Western Reserve University, Trailhead emerged from the research of CSO/CTO and founder Dr. Jan Jensen. Trailhead creates optimized human cells at scale with its proprietary High-Dimensional Design-of-Experiments (HD-DoE ®) platform, integrating advanced mathematical modeling with high-throughput robotic manufacturing. This innovative system allows Trailhead to develop specialized, high-quality iPSC-derived human cells for drug discovery and cell-based therapies. TrailBio ® A9 Dopaminergic Neurons represent one of many specialized human cell types emerging from this platform, with additional cell models expected in the near future. Learn more about Trailhead Biosystems, TrailBio ® A9 Dopaminergic Neurons and HD-DoE ® at For more information, please contact:
Yahoo
22-06-2025
- Business
- Yahoo
Caitlin Clark's Former Coach Makes Big Announcement on Monday
Caitlin Clark's Former Coach Makes Big Announcement on Monday originally appeared on Athlon Sports. U.S. District Judge Claudia Wilken granted final approval to the landmark House v. NCAA antitrust settlement on Friday, clearing the way for Division I programs to share revenues directly with student-athletes beginning July 1, 2025. Advertisement Under the new framework, institutions may allocate up to $20.5 million in revenue sharing in 2025-26, with approximately 5% reserved for women's college basketball, a substantial shift from prior amateurism rules. Following the news, Iowa Women's Basketball took to Instagram on Monday to share a clear message from head coach Jan Jensen. Iowa Athletics launched the Women's Basketball Flight Fund, designed to "recruit and retain our student-athletes' and ensure the Hawkeyes "stay among the elite in our sport." She thanked fans and emphasized "innovative leadership" in creating a mechanism for sustained competitiveness at the highest level. Advertisement The post was accompanied by the caption, "Striving to be the best! 👊🔗 Link in bio #Hawkeyes." Jensen joined Lisa Bluder's staff at Iowa in 2000, serving as associate head coach for more than two decades. Over that time, she played a central role in landing Megan Gustafson and Caitlin Clark, both eventual All-Americans. As associate HC, she helped Iowa reach consecutive national championship games (2023, 2024) and secured five Big Ten tournament crowns. She was named WBCA Assistant Coach of the Year in 2023 and picked up the Maggie Dixon Award as top rookie head coach in 2025 after inheriting the team following Bluder's retirement. Former Iowa Hawkeyes guard Caitlin Clark and associate head coach Jan Lee-USA TODAY Sports via Imagn Images. Clark, meanwhile, concluded her Iowa career by shattering the Division I scoring record (for men or women), finishing with 3,951 career points. Advertisement Over four years with the Hawkeyes, she was a four-time USBWA first-team All-American, a three-time Big Ten Player of the Year and a three-time NCAA season scoring and assists leader. Clark also collected back-to-back AP Player of the Year, Naismith Award, Wooden Award, Honda Sports Award and USBWA Player of the Year honors in 2023 and 2024. Related: Dawn Staley Sends Strong Message to Vanessa Bryant on Saturday This story was originally reported by Athlon Sports on Jun 9, 2025, where it first appeared.
Yahoo
16-06-2025
- Sport
- Yahoo
Iowa women's basketball opens summer practices
As the exciting incoming class for the Iowa women's basketball program moved in over the weekend, the team began its summer practices on Sunday as the Hawkeyes tune up for the impending 2025-26 season. While Iowa closed out the 2024-25 campaign with a 10-8 record within the Big Ten and 23-11 overall, the Hawkeyes' last 15 games saw the team go on a scorching hot 11-3 run before dropping their second-round matchup to Oklahoma in the NCAA Tournament. Entering her second season as head coach, Jan Jensen looks to capitalize on the Hawkeyes' late-season momentum with a retooled group of talented players joining the team. Headlining the exciting group of newcomers are five-star guard Addie Deal, who is joined by fellow guards Jouney Houston, Chazadi 'Chit-Chat' Wright, and center Layla Hayes. Among those four, Wright is the lone addition with previous collegiate experience as the sophomore played at Georgia Tech last season before joining Iowa through the transfer portal. Advertisement While the team endured some growing pains last year with a new head coach, conference expansion, and inopportune injuries, the Hawkeyes hope the lessons learned from last season will allow the group to take the next step towards regaining their spot amongst the conference's and nation's elites. As the summer practices move along and the summer months turn to fall, the anticipation for another memorable Hawkeyes season will only grow stronger by the day. Contact/Follow us @HawkeyesWire on X (formerly Twitter) and like our page on Facebook to follow ongoing coverage of Iowa news, notes, and opinions. Follow Scout on X: @SpringgateNews This article originally appeared on Hawkeyes Wire: Iowa women's basketball opens summer practices
