Study Warns of Weight Regain After Stopping Popular Weight Loss Medications - Jordan News
Among the most well-known of these drugs are Ozempic and Wegovy, which both contain the active ingredient semaglutide, along with other approved medications aimed at controlling weight and improving overall health. Numerous studies and clinical trials are being conducted to evaluate the efficacy of these drugs, their effects on the body, and the challenges related to their use and discontinuation. اضافة اعلان In this context, a new study has found that patients taking weight-loss medications like Ozempic and Wegovy may regain the weight they lost within a few weeks of stopping the medication. The research team, including scientists from Peking University People's Hospital in China, analyzed data from 11 clinical trials involving around 2,500 participants. They found that most patients gradually regained weight after ending the treatment. The review, published in BMC Medicine, revealed that weight regain typically begins around eight weeks after stopping the medication and may continue for up to 20 weeks before stabilizing. Most of the trials focused on semaglutide, one of six approved medications for treating obesity in adults. Originally developed to treat type 2 diabetes, semaglutide has gained widespread popularity as an effective weight loss drug. The findings showed that the substantial weight loss achieved through these medications is often followed by a rapid regain once the drugs are discontinued. Researchers also observed that factors such as the type of medication and adherence to lifestyle changes—including diet and exercise—significantly impacted the rate of weight regain. For instance, patients who took tirzepatide for 36 weeks regained nearly half of the lost weight after switching to a placebo. The researchers stressed the need for long-term studies to better understand the factors influencing weight change after discontinuing weight loss medications, with the goal of improving obesity treatment strategies and preventing weight regain.
Source: The Independent
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Jordan News
5 days ago
- Jordan News
Study Warns of Weight Regain After Stopping Popular Weight Loss Medications - Jordan News
Weight loss medications are increasingly being used as an effective treatment for obesity, significantly helping adults reduce excess weight. Among the most well-known of these drugs are Ozempic and Wegovy, which both contain the active ingredient semaglutide, along with other approved medications aimed at controlling weight and improving overall health. Numerous studies and clinical trials are being conducted to evaluate the efficacy of these drugs, their effects on the body, and the challenges related to their use and discontinuation. اضافة اعلان In this context, a new study has found that patients taking weight-loss medications like Ozempic and Wegovy may regain the weight they lost within a few weeks of stopping the medication. The research team, including scientists from Peking University People's Hospital in China, analyzed data from 11 clinical trials involving around 2,500 participants. They found that most patients gradually regained weight after ending the treatment. The review, published in BMC Medicine, revealed that weight regain typically begins around eight weeks after stopping the medication and may continue for up to 20 weeks before stabilizing. Most of the trials focused on semaglutide, one of six approved medications for treating obesity in adults. Originally developed to treat type 2 diabetes, semaglutide has gained widespread popularity as an effective weight loss drug. The findings showed that the substantial weight loss achieved through these medications is often followed by a rapid regain once the drugs are discontinued. Researchers also observed that factors such as the type of medication and adherence to lifestyle changes—including diet and exercise—significantly impacted the rate of weight regain. For instance, patients who took tirzepatide for 36 weeks regained nearly half of the lost weight after switching to a placebo. The researchers stressed the need for long-term studies to better understand the factors influencing weight change after discontinuing weight loss medications, with the goal of improving obesity treatment strategies and preventing weight regain. Source: The Independent
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Foods That Become Healthier When Cooled - Jordan News
Foods That Become Healthier When Cooled Recent nutritional research suggests that cooling certain foods after cooking can actually enhance their nutritional value — primarily by increasing their content of resistant starch. اضافة اعلان Resistant starch is a type of carbohydrate that digests slowly, supporting digestive health and helping to regulate blood sugar levels. According to here are eight common foods that become more beneficial when cooled: 1. White Rice Once cooked and then cooled, some of the starch in rice converts into resistant starch. This benefits gut health and reduces the risk of type 2 diabetes. It works well in cold dishes like crab sushi or rice salads with vegetables. 2. Chilled Oats Known as "overnight oats," they are soaked in milk or milk alternatives along with fruits and nuts, then refrigerated for several hours. This method boosts the resistant starch content, supporting gut health. 3. Chilled Potatoes Boiling or baking potatoes and then cooling them increases their resistant starch content. This makes them more beneficial for blood sugar control. They're ideal in healthy potato salads with Greek yogurt. 4. Dill A study in the Antioxidants journal showed that chilling dill increases its antioxidant compounds (phenolic acids), enhancing its protective effects against chronic diseases. 5. Pasta Cooked and cooled pasta produces resistant starch as well, making it perfect for cold pasta salads rich in vegetables. 6. Barley Cooled barley becomes a good source of resistant starch and can be used in nutritious salads or as a side dish alternative to rice. 7. Beans Cooling cooked beans increases their resistant starch content, along with their natural protein and fiber. They can be added to salads or eaten as a healthy snack. 8. Chilled Bread Storing fresh bread in the fridge for about a week raises its resistant starch levels. It can then be used for making healthy cold sandwiches. Source: The Independent
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Ozempic, Wegovy linked to rare vision-loss disorder, EU regulator warns
The European Medicines Agency (EMA) said on Friday that Novo Nordisk's popular drugs Ozempic and Wegovy may, in very rare cases, cause a serious eye disorder that can lead to vision loss. Following a months-long safety review, the EMA's Pharmacovigilance Risk Assessment Committee concluded that semaglutide, the active ingredient in Ozempic, Wegovy, and Rybelsus, is associated with rare occurrences of non-arteritic anterior ischemic optic neuropathy (NAION), a condition caused by reduced blood flow to the optic nerve. The disorder is the second-most common cause of blindness due to optic nerve damage, after glaucoma. The EMA said NAION could affect up to 1 in 10,000 patients taking semaglutide and that the risk of developing the condition is roughly double that of individuals not using the medication. The EMA began investigating the link between semaglutide and NAION in December 2023 after earlier studies signaled a possible connection. One large observational study involving nearly 350,000 type 2 diabetes patients showed that long-term semaglutide use more than doubled the risk of developing NAION compared to those on alternative treatments. This marks the first time a regulatory body has formally acknowledged the connection, though academic research had previously pointed to the risk. Semaglutide is part of a class of drugs known as GLP-1 receptor agonists, which regulate blood sugar and promote a feeling of fullness, making them widely prescribed for both diabetes management and weight loss. The EMA has recommended that Novo Nordisk update prescribing information for all semaglutide-containing products to include NAION as a potential side effect, categorized as 'very rare.'
