Latest news with #PoonamSharma
Hindustan Times
01-07-2025
- Health
- Hindustan Times
AIIMS doctor says cancer relapse can be prevented if you start with these 4 lifestyle habits
Cancer relapse refers to the reappearance of malignant cells after a period of remission. It can occur months to decades post-treatment, with metastatic latency (dormant cancer cells) being a key mechanism. Cancer can come back years later, even after a clean report but you can prevent it by adopting these 4 lifestyle modifications.(Image by Pexels) In an interview with HT Lifestyle, Dr Poonam Sharma, Associate Professor and Officiating Head - Department of Pathology at AIIMS Jammu, shared that relapse rates vary by cancer type: Breast cancer shows 10% locoregional relapse rates despite optimal treatment Non-metastatic Ewing sarcoma has 2-10 year relapse windows in many patients Early relapsed breast cancer (within 8 months) correlates with poor prognosis. Dr Poonam Sharma answered, 'Our genes can significantly affect the chances of a cancer returning. Some people inherit genetic mutations that make their cancer more likely to come back. For instance, certain mutations—such as those in the TP53 or PIK3CA genes—are commonly found in relapsed breast cancers. In other cases, new genetic changes can develop in cancer cells over time, making them more aggressive or resistant to treatment.' Findings suggest that night shifts disrupt natural 24-hour rhythms in the activity of certain cancer-related genes, making night shift workers more vulnerable to DNA damage while also causing the body's DNA repair mechanisms to be mistimed to deal with that damage.(Unsplash) She revealed, 'Researchers have also found that some inherited genetic variants can explain why certain groups of people are at higher risk for relapse. For example, specific genetic markers help explain why relapse rates differ between racial groups in childhood leukemia.' Genetics and cancer relapse Genetics matter more in some cancers than others. Dr Poonam Sharma explained, 'In breast cancer, for example, researchers have found that certain gene mutations are common in cases where the cancer comes back. Ewing sarcoma, a rare bone cancer, can also be more likely to return if certain genes are active. Bladder cancer and some childhood leukemias (like acute lymphoblastic leukemia) are also influenced by specific genetic factors.' The connection between diet and gene regulation highlights the potential for dietary interventions in preventing colorectal cancer.(AdobeStock) She added, 'In these cancers, knowing about your genetic makeup can help doctors personalize your care. For example, if you have a gene that increases your risk of relapse, your doctor might recommend more frequent check-ups or different treatments to help keep the cancer from returning.' Lifestyle and cancer relapse According to Dr Poonam Sharma, modifiable factors significantly affect outcomes: Diet: Western dietary patterns increase recurrence risk vs Mediterranean diets. Weight management: Obesity correlates with 30-40% higher mortality in survivors. Physical activity: Reduces all-cause mortality by 43% in cancer survivors. Substance avoidance: Smoking cessation lowers recurrence risk by 22%. Dr Poonam Sharma pointed out, 'While genetics determine baseline risk, lifestyle modifications can mitigate approximately 30% of relapse risk through metabolic regulation and immune modulation. Breast and colorectal cancers show particularly strong lifestyle interaction effects.' Note to readers: This article is for informational purposes only and not a substitute for professional medical advice. Always seek the advice of your doctor with any questions about a medical condition.
Hans India
10-06-2025
- Business
- Hans India
FLO hyderabad announces 5th edition of StyleTatva – now powered by MSME
FLO Hyderabad, the women's wing of FICCI, proudly announced the 5th edition of its flagship fashion and lifestyle exhibition, 'StyleTatva', to be held on June 13–14, 2025, at HITEX Hall 2 from 10 am to 8 pm. This year marks a milestone as the event is officially powered by the Ministry of MSME, Government of India—demonstrating FLO's deep commitment to empowering women entrepreneurs and artisans. Featuring 205 curated exhibitors from across the country, 'StyleTatva' 2025 will showcase a vibrant mix of fashion, lifestyle, décor, and artisanal products. Over 10,000 visitors are expected to attend. Entry is free via WhatsApp invite, or ₹100 at the gate. The exhibition will be inaugurated by Hyderabad Mayor Gadwal Vijayalakshmi, with Poonam Sharma, FLO National President, and celebrity fashion draper Dolly Jain as guests of honour. Femina Miss India 2023 and Miss World Top 20 finalist Nandini Gupta graced the pre-event press conference, expressing admiration for FLO's initiative: 'When women come together passionately, incredible things happen. 'StyleTatva' is a wonderful event with a great purpose.' A key highlight is the 'Initiative Pavilion' showcasing the revival of the ancient 'Dokra' craft from Adilabad. Known for its unique lost-wax metal casting, 'Dokra' art is being revived through design innovation and market linkages. FLO will premiere a documentary on the artisans and their stories during the event. In alignment with social impact, FLO is offering free stalls to Telangana weavers, prison-based livelihood programs, and social sector artisans. An MSME desk at the venue will also help entrepreneurs register for Udyam and access benefits, including Rs 54,000 stall reimbursement and Rs 25,000 for incidentals under the government scheme. 'StyleTatva is where purpose meets profit,' said FLO Chairperson Prathibha Kunda. 'With support from MSME, we're fuelling women-led growth and preserving our heritage.' Proceeds from the exhibition will fund FLO Hyderabad's social impact projects like the 'Bhongir Skill Centre', digital skilling, and vocational training for women—creating sustainable livelihoods and supporting craft heritage revival across Telangana.
Time of India
24-04-2025
- General
- Time of India
An all-women brick unit to end gender inequality in real estate
1 2 Lucknow: A group of 30 women in Lucknow's backyard are working hard to create UP's first all-woman unit that will manufacture high-strength green concrete eco-bricks . The initiative, called Nirman by Women, is led by a private company named Ventura Prefab with the support of the State Rural Livelihood Mission (UPSRLM). It is also an effort to challenge gender inequality in India's real estate and construction sector. This is significant considering that the presence of women in India's real estate and construction sector stands at an abysmal 12%, and that too in secondary roles with lower wages. However, in this pilot, women are being trained in primary jobs such as machine operation, batch mixing, and concrete moulding, among others, which were traditionally meant for men. Chief Secretary UP, Manoj Kumar Singh, along with senior officials from the UPSRLM, visited the factory on Thursday. An interaction with the trainee women brought to the fore stories of grit and awe. Poonam Sharma, a woman in her mid-20s, carried her six-month-old daughter to start a new life, away from her alcohol-addict husband. "I am a victim of a patriarchal mindset and gender bias, but I don't want my daughter to inherit the same fate. This training came as an opportunity to me, and I availed it to carve my individual and independent identity," said the woman, whose aunt takes care of the baby when she is working in the factory. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Trade Bitcoin & Ethereum – No Wallet Needed! IC Markets Start Now Undo Manta Devi of Chak Prithvirajpur village rebelled against her husband and in-laws to learn the skill. "Work guarantees the flow of money, not lamentations," remarked the lean and thin woman. Kavita Bhatnagar, who is associated with the training, informed that it took a lot of effort to convince the women to join the programme. "There were all kinds of barriers. Many women had no confidence; others felt that they weren't as strong as men. Several interactions with the women through self-help group lead ladies helped to iron out the doubts," she recalled. But there were women who saw the opportunity as a chance to chase their dream of financial self-reliance. Akanksha Singh, an 18-year-old girl awaiting her board result, is a case in point. "My father is a cancer patient. We sold off our land for his treatment. My financial independence is necessary to lessen the burden on my family," she said, hoping to launch a start-up of her own through various entrepreneurial schemes of the state govt. Rajani Devi of Khasrawa village wants a better future for her children and is aware that the single income of her husband can never ensure the continuity of education. Avadheesh Srivastava, who holds a master's degree in civil engineering and is training these women, was both shocked and amazed upon meeting his 'students'. His first realisation was that they had very limited foundational understanding of science while their minds were full of questions that were never answered. Machine handler and trainer Kuldeep said, "Women are naturally gritty, and this lot proved it to me. They were not scared to try anything. The moment they understood the science behind the machine, they took control of it and practised it till perfection." Mother of this initiative, Rashmi Sinha, who has worked closely on women's issues in various places, including the United Nations, said that the training would end in a few weeks, but the journey of change has just begun.
