Latest news with #Princeton-led


Axios
5 days ago
- Health
- Axios
Researchers identify four distinct types of autism
There are four distinct varieties of autism, each linked to unique genetic profiles — a discovery that could offer new insights into the neurodevelopmental condition, according to a new study in Nature Genetics. Why it matters: The findings come as Health Secretary Robert F. Kennedy is pushing federal efforts to identify an " environmental" cause for increased autism incidence by September. Driving the news: A Princeton-led research team examined data from more than 5,000 children in SPARK, an autism cohort study funded by the Simons Foundation. After analyzing more than 230 traits including social interactions and repetitive behaviors, they identified four subtypes: "social and behavioral challenges," "mixed ASD with developmental delay," "moderate challenges" and "broadly affected." They then linked the subtypes to distinct genetic mutations, identifying divergent biological processes in each. For example, children in the "broadly affected" group showed the highest proportion of mutations not inherited from either parent, while the "mixed ASD with developmental delay" group was more likely to carry rare inherited genetic variants. Autism is known to be highly heritable, with many implicated genes. But the researchers said standard genetic testing only explains about 20% of cases. What they're saying:"What we're seeing is not just one biological story of autism, but multiple distinct narratives," said Natalie Sauerwald, associate research scientist at the Flatiron Institute and co-lead author, in a statement.


Axios
03-07-2025
- Business
- Axios
What's next as energy overhaul heads for Trump's desk
Here are a few things worth watching now that the GOP budget plan is on the cusp of final passage and President Trump's signature. Renewables' and EVs' path ahead. Solar, wind and EVs face an aggressive loss of incentives in the plan. State of play: The Princeton-led REPEAT Project is out with preliminary estimates of the bill, which shakes up the landscape for many kinds of tech. The big picture: It sees $500 billion less in cumulative electricity and "clean fuels" investment from 2025-2035 than what would otherwise occur. What we're watching: The analysis sees 72 fewer gigawatts of wind and solar capacity additions by 2030. The midterm politics. Democrats will hit Republicans over reduced low-carbon energy investment in red states. Yes, but: The political salience of clean energy is hardly clear — the IRA did not appear to provide a big 2024 lift — so the midterms are the next test. Oil industry appetites. The bill expands and speeds up leasing, and under more favorable terms. That includes offshore and Arctic regions in Alaska. The big picture: These and other provisions reverse what Republicans and the industry call undue restrictions that Biden officials imposed on domestic energy. Tesla's tough road. In addition to scuttling consumer purchase credits, the bill ends civil penalties on automakers that don't meet fuel efficiency rules.


Time of India
18-05-2025
- Politics
- Time of India
Why Pakistan's middle class backs terror while poor suffer from it
Why Pakistan's middle class backs terror while poor suffer from it Team TOI Plus Updated: May 18, 2025, 18:41 IST IST A 2012 study, which has acquired new relevance after Pahalgam and Operation Sindoor, reveals that Pakistan's urban middle class — shielded from violence and ideologically invested — sustains extremist groups For years, the dominant explanation for terrorism in Pakistan has rested on a simple idea: that poverty breeds radicalism. It is a narrative among global policy experts that has shaped the direction of billions of dollars in international aid and development programmes. Now, with Pahalgam and India's Operation Sindoor reigniting the debate over cross-border militancy, a 2012 Princeton-led study has acquired fresh relevance, revealing that the true drivers of extremism may lie closer to comfort than crisis.