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Newsweek
4 days ago
- Health
- Newsweek
Children Consuming Common Sweeteners Face Higher Early Puberty Risk
Based on facts, either observed and verified firsthand by the reporter, or reported and verified from knowledgeable sources. Newsweek AI is in beta. Translations may contain inaccuracies—please refer to the original content. Common sweeteners found in foods and drinks may significantly increase the risk of early puberty in children, new research shows. The findings come from a large-scale study that was presented on today at ENDO 2025, the Endocrine Society's annual meeting in San Francisco. Researchers analyzed data from more than 1,400 adolescents and found a strong link between sweetener consumption and central precocious puberty, a condition where puberty begins unusually early—typically before age eight in girls and nine in boys. Central precocious puberty is becoming more common worldwide and can have lasting health consequences, including emotional challenges, shorter adult height and an increased risk of reproductive and metabolic disorders later in life. The increased risk from sweeteners was also notably elevated among teens with specific genetic markers associated with early puberty onset. Close Up Of Girl Drinking Sugary Fizzy Soda From Glass With Straw Close Up Of Girl Drinking Sugary Fizzy Soda From Glass With Straw Daisy-Daisy "This study is one of the first to connect modern dietary habits—specifically sweetener intake—with both genetic factors and early puberty development in a large, real-world cohort," said Yang-Ching Chen, M.D., Ph.D., of Taipei Municipal Wan Fang Hospital and Taipei Medical University in Taipei, Taiwan. The study, part of the ongoing Taiwan Pubertal Longitudinal Study (TPLS) launched in 2018, analyzed data on 1,407 adolescents, of whom 481 were diagnosed with central precocious puberty. Researchers assessed dietary intake using questionnaires and urine testing and measured genetic risk using polygenic risk scores based on 19 genes related to early puberty. The study revealed gender-specific effects of common sweeteners, which include aspartame, sucralose, glycyrrhizin (a compound found in licorice) and added sugars. In girls, consumption of glycyrrhizin, sucralose and added sugars was linked to a higher risk of central precocious puberty. In boys, sucralose stood out as the most significant sweetener associated with early puberty onset. These sweeteners are commonly found in a wide range of everyday foods and drinks, including diet sodas, flavored yogurts, sugar-free gums, protein bars, cereals and even some children's medications. Researchers also found a dose-response relationship: the more sweeteners consumed, the higher the risk. The findings build on Chen's earlier work, which showed that sweeteners can disrupt hormonal regulation and gut microbiota balance. For instance, acesulfame potassium (AceK), another common artificial sweetener, was previously shown to activate brain cell receptors involved in "sweet taste" pathways, increasing the release of puberty-related hormones and stress molecules. Glycyrrhizin was also found to alter gut bacteria and suppress key genes that regulate puberty timing. "This suggests that what children eat and drink, especially products with sweeteners, may have a surprising and powerful impact on their development," Chen said. The findings could have far-reaching implications for dietary guidelines and pediatric care. Chen emphasized that monitoring sweetener intake and considering a child's genetic predisposition may be critical in preventing early puberty and its associated long-term health risks. "These results are directly relevant to families, pediatricians, and public health authorities," Chen said. "They suggest that screening for genetic risk and moderating sweetener intake could help prevent early puberty and its long-term health consequences." Do you have a tip on a health story that Newsweek should be covering? Do you have a question about children's health? Let us know via health@
Yahoo
05-02-2025
- Business
- Yahoo
Thornburg Expands Active ETF Lineup with Two Fixed Income ETFs
SANTA FE, N.M., Feb. 5, 2025 /PRNewswire/ -- Thornburg Investment Management ("Thornburg"), a global investment firm that oversees $46 billion in assets1, today announced the launch of two active fixed income exchange-traded funds (ETFs), Thornburg Core Plus Bond ETF (Nasdaq: TPLS) and Thornburg Multi Sector Bond ETF (Nasdaq: TMB). Both ETFs begin trading today. Last month, Thornburg launched its first two active ETFs, Thornburg International Equity ETF (Nasdaq: TXUE) and Thornburg International Growth ETF (Nasdaq: TXUG). These equity funds have already attracted over $80 million in investments. "With over $80 million in client inflows, it's clear that investors look to Thornburg's four decades of investing excellence and prudent risk management to achieve their long-term financial goals," said Thornburg CEO Mark Zinkula. "Expanding our ETF lineup with two fixed income ETFs reflects our commitment to meeting long-term client demand." Thornburg Core Plus Bond ETF, managed by Lon Erickson, CFA, and Christian Hoffmann, CFA, is actively managed and seeks total return, consisting of income and capital appreciation. It manages risk through a portfolio comprised primarily of high-quality investment-grade bonds, complemented by up to 25% in below-investment-grade securities. Thornburg Multi Sector Bond ETF, managed by Messrs. Erickson and Hoffmann as well as Ali Hassan, CFA, seeks total return, consisting of income and capital appreciation, with active management designed to adapt to changing markets. The fund's exposure across fixed income sectors, including high yield and foreign securities, is based on the team's views on relative value and will help drive income and return potential. "At its core, Thornburg is an active manager," said Thornburg Global Head of Distribution Jesse Brownell. "We always put our clients first, so we took a deliberate and strategic approach to entering the competitive active ETF market. The positive response to our ETFs is exciting and demonstrates that Thornburg's approach to product development resonates with investors." Learn more about Thornburg ETFs at About Thornburg Thornburg Investment Management ("Thornburg") is an active, high-conviction manager of equities, fixed income, multi-asset and alternative solutions. As a privately owned firm and with $46 billion1 in client assets as of January 31, 2025, Thornburg serves institutions, financial professionals and investors worldwide. The firm offers mutual funds, ETFs, closed-end funds, separate accounts and UCITS funds. Thornburg was founded in 1982 and is headquartered in Santa Fe, New Mexico with an additional office in Hong Kong. For more information, visit or call 877 215 1330. Media Inquiries Michael CorraoDirector of Global Communications Thornburg Investment ManagementTel: +1 505 467 5345 Email: mcorrao@ Important Disclosures Before investing, carefully consider the Fund's investment goals, risks, charges, and expenses. For a prospectus or summary prospectus containing this and other information, contact your financial advisor or visit Read them carefully before investing. Exchange Traded Funds (ETF) are bought and sold through exchange trading at market prices (not NAV) and are not individually redeemed from a Fund. Shares may trade at a premium or discount to their NAV in the secondary market. Brokerage commissions will reduce returns. Each Fund is an actively managed ETF that does not seek to replicate the performance of a specified index. To determine whether to buy or sell a security, the portfolio managers consider, among other things, various fund requirements and standards, along with economic conditions, alternative investments, interest rates and various credit metrics. If the portfolio manager considerations are inaccurate or misapplied, the fund's performance may suffer. Investments carry risks, including possible loss of principal. Additional risks may be associated with investments outside the United States, especially in emerging markets, including currency fluctuations, illiquidity, volatility, and political and economic risks. Investments in small- and mid-capitalization companies may increase the risk of greater price fluctuations. Risks associated with investing in Thornburg ETFs may include: (1) New and Smaller Sized Fund Risk, (2) Investment Adviser Risk and (3) Derivatives Risk. Additional risks associated with investing in TXUE and TXUG may include: (1) Equity Risk, (2) Risks Affecting Specific Countries or Regions and (3) Market and Economic Risk. Additional risks associated with investing in TXUG may include: (1) Growth Company Risk and (2) Small and Mid-Cap Company Risk. Additional risks associated with investing in TPLS and TMB may include: (1) Credit Risk, (2) High Yield Risk, (3) Interest Rate Risk and (4) Market and Economic Risk. Additional risks associated with investing in TPLS may include: (1) Emerging Markets Risk. More information regarding the risks associated with investing in Thornburg ETFs can be found in the fund prospectuses. Please see our glossary for a definition of terms. Thornburg ETFs are distributed by ALPS Distributors, Inc. ___________________ 1 Includes $45 billion in assets under management and $1 billion in assets under advisement as of January 31, 2025. View original content to download multimedia: SOURCE Thornburg Investment Management
