Latest news with #WashingtonDC
Yahoo
32 minutes ago
- Business
- Yahoo
BioMarin's ROCTAVIAN Shows Sustained Efficacy, Safety Over 5 Years for Severe Hemophilia A
BioMarin Pharmaceutical Inc. (NASDAQ:BMRN) is one of the most undervalued US stocks according to analysts. On June 24, BioMarin Pharmaceutical Inc. presented new 5-year data from its Phase 3 GENEr8-1 trial at the 33rd Congress of the International Society on Thrombosis and Haemostasis/ISTH in Washington, D.C., which took place from June 21 to 25. The data reinforced the long-term efficacy and safety of ROCTAVIAN (valoctocogene roxaparvovec-rvox) as a gene therapy for severe hemophilia A. The GENEr8-1 trial is the longest and largest hemophilia gene therapy study to date, and demonstrated sustained Factor VIII (FVIII) expression and durable bleed control 5 years after a single treatment with ROCTAVIAN. A pharmaceutical plant manufacturing a proprietary synthetic oral form of a C-type natriuretic peptide. FVIII activity remained consistent with previously reported results. Importantly, no new safety signals were observed over the 5-year study period. Across all 134 participants who received ROCTAVIAN in the study, there were no cases of FVIII inhibitors or thromboembolic events, and no treatment-related malignancies were observed. BioMarin Pharmaceutical Inc. (NASDAQ:BMRN) is a biotechnology company that develops and commercializes therapies for life-threatening rare diseases and medical conditions internationally. While we acknowledge the potential of BMRN as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the . READ NEXT: and . Disclosure: None. This article is originally published at Insider Monkey. Sign in to access your portfolio
Sky News
3 hours ago
- Politics
- Sky News
Why critics believe Trump's big win in Supreme Court is 'terrifying step towards authoritarianism'
As the president himself said, this was a "giant" of a decision - a significant moment to end a week of whiplash-inducing news. The decision by the US Supreme Court is a big win for President Donald Trump. By a majority of 6-3, the highest court in the land has ruled that federal judges have been overreaching in their authority by blocking or freezing the executive orders issued by the president. Over the last few months, a series of presidential actions by Trump have been blocked by injunctions issued by federal district judges. The federal judges, branded "radical leftist lunatics" by the president, have ruled on numerous individual cases, most involving immigration. They have then applied their rulings as nationwide injunctions - thus blocking the Trump administration's policies. "It was a grave threat to democracy frankly," the president said at a hastily arranged news conference in the White House briefing room. "Instead of merely ruling on the immediate case before them, these judges have attempted to dictate the law for the entire nation," he said. In simple terms, this ruling, from a Supreme Court weighted towards conservative judges, frees up the president to push on with his agenda, less opposed by the courts. "This is such a big day…," the president said. "It gives power back to people that should have it, including Congress, including the presidency, and it only takes bad power away from judges. It takes bad power, sick power and unfair power. "And it's really going to be... a very monumental decision." The country's most senior member of the Democratic Party was to the point with his reaction to the ruling. Senate minority leader Chuck Schumer called it "an unprecedented and terrifying step toward authoritarianism, a grave danger to our democracy, and a predictable move from this extremist MAGA court". In a statement, Schumer wrote: "By weakening the power of district courts to check the presidency, the Court is not defending the Constitution - it's defacing it. "This ruling hands Donald Trump yet another green light in his crusade to unravel the foundations of American democracy." 2:57 Federal power in the US is, constitutionally, split equally between the three branches of government - the executive branch (the presidency), the legislative branch (Congress) and the judiciary (the Supreme Court and other federal courts). They are designed to ensure a separation of power and to ensure that no single branch becomes too powerful. This ruling was prompted by a case brought over an executive order issued by President Trump on his inauguration day to end birthright citizenship - that constitutional right to be an American citizen if born here. A federal judge froze the decision, ruling it to be in defiance of the 14th Amendment of the Constitution. The Supreme Court has deferred its judgement on this particular case, instead ruling more broadly on the powers of the federal judges. The court was divided along ideological lines, with conservatives in the majority and liberals in dissent. 👉 Follow Trump100 on your podcast app 👈 In her dissent, liberal Justice Ketanji Brown Jackson wrote: "As I understand the concern, in this clash over the respective powers of two coordinate branches of Government, the majority sees a power grab - but not by a presumably lawless Executive choosing to act in a manner that flouts the plain text of the Constitution. "Instead, to the majority, the power-hungry actors are... (wait for it)... the district courts." Another liberal Justice, Sonia Sotomayor, described the majority ruling by her fellow justices as: "Nothing less than an open invitation for the government to bypass the constitution." Conservative Justice Amy Coney Barrett, who Trump appointed during his first term, shifting the balance of left-right power in the court, led this particular ruling. Writing for the majority, she said: "When a court concludes that the executive branch has acted unlawfully, the answer is not for the court to exceed its power, too." The focus now for those who deplore this decision will be to apply 'class action' - to file lawsuits on behalf of a large group of people rather than applying a single case to the whole nation. There is no question though that the president and his team will feel significantly emboldened to push through their policy agenda with fewer blocks and barriers. The ruling ends a giddy week for the president. 0:51 Last Saturday he ordered the US military to bomb Iran's nuclear sites. Within two days he had forced both Israel and Iran to a ceasefire. By mid-week he was in The Hague for the NATO summit where the alliance members had agreed to his defence spending demands. At an Oval Office event late on Friday, where he presided over the signing of a peace agreement between the Democratic Republic of Congo and Rwanda, he also hinted at a possible ceasefire "within a week" in Gaza.
Daily Mail
3 hours ago
- Politics
- Daily Mail
BREAKING NEWS Pam Bondi knifes January 6 prosecutors in late-night bloodbath
The Trump administration took revenge against at least three federal prosecutors who worked on cases against January 6 rioters by firing them. Attorney General Pam Bondi sacked the prosecutors on Friday, telling them they were 'removed from federal service effective immediately.' In a copy of one of the dismissal letters first reported by NBC News, Bondi did not specify why the prosecutors were out of the job. The firings are the first time that career prosecutors who investigated the riot at the Capitol four years ago had been laid off, but it is far from Trump's first act of retribution over the violent protests since he retook the White House. Soon after his inauguration, Trump fired several probationary federal prosecutors - those who were either recently hired or in new positions - who had worked the January 6 cases. The president also pardoned all his supporters who were arrested during the January 6 riots, sparking backlash from critics as even some convicted of violently assaulting police officers were freed. Trump also fired probationary prosecutors who aided special counsel Jack Smith's investigation into whether the president attempted to unlawfully overturn his loss in the 2020 presidential election. The president's use of the Justice Department has come under scrutiny in recent months as he has been accused of using it to carry out personal vendettas and to aid his political supporters. Friday's firings reportedly came at a tense time at the Justice Department as Trump's handling of the January 6 case causes ire among career federal workers. Insiders in the DOJ told NBC News that the apparent targeting of prosecutors who had investigated the president has upended the department. One federal law enforcement official told the outlet that they found the firings 'horrifying', as others said it would make them hesitant to engage in possible investigations into the White House. 'To fire them, without explanation, is a slap in the face not only to them, but to all career DOJ prosecutors,' the official said. 'No one is safe from this administration's whims and impulses. 'And the public certainly is not served by the continued brain drain of DOJ — we are losing the best among us every day.' Bondi's move came the same day that she celebrated a Supreme Court ruling that decided that individual judges lack the power to issue nationwide injunctions - a historic ruling in a case about the right to birthright citizenship. The ruling was seen as a big victory for Trump as it allows his executive order halting birthright citizenship for children of undocumented immigrants to take effect in states and jurisdictions that did not directly challenge his action in court. It could mean citizenship rules vary from state to state, pending ongoing litigation. The court ruled 6-3 in favor of Trump, with all six conservative justices - including the three he appointed - siding with the president. Speaking at the White House, Trump said: 'This was a big one. Amazing decision, one we're very happy about. This really brings back the Constitution. This is what it's all about.' Bondi joined Trump on stage to mark the victory, saying that the ruling meant 'not one district court judge can think they're an emperor over this administration and his executive powers, and why the people of the United States elected him.'
Daily Mail
3 hours ago
- Politics
- Daily Mail
Pam Bondi knifes January 6 prosecutors in late-night bloodbath
The Trump administration took revenge against at least three federal prosecutors who worked on cases against January 6 rioters by firing them. Attorney General Pam Bondi sacked the prosecutors on Friday, telling them they were 'removed from federal service effective immediately.' In a copy of one of the dismissal letters first reported by NBC News, Bondi did not specify why the prosecutors were out of the job. The firings are the first time that career prosecutors who investigated the riot at the Capitol four years ago had been laid off, but it is far from Trump's first act of retribution over the violent protests since he retook the White House. Soon after his inauguration, Trump fired several probationary federal prosecutors - those who were either recently hired or in new positions - who had worked the January 6 cases. The president also pardoned all his supporters who were arrested during the January 6 riots, sparking backlash from critics as even some convicted of violently assaulting police officers were freed. Trump also fired probationary prosecutors who aided special counsel Jack Smith's investigation into whether the president attempted to unlawfully overturn his loss in the 2020 presidential election. The president's use of the Justice Department has come under scrutiny in recent months as he has been accused of using it to carry out personal vendettas and to aid his political supporters. Friday's firings reportedly came at a tense time at the Justice Department as Trump's handling of the January 6 case causes ire among career federal workers. Insiders in the DOJ told NBC News that the apparent targeting of prosecutors who had investigated the president has upended the department. One federal law enforcement official told the outlet that they found the firings 'horrifying', as others said it would make them hesitant to engage in possible investigations into the White House. 'To fire them, without explanation, is a slap in the face not only to them, but to all career DOJ prosecutors,' the official said. 'No one is safe from this administration's whims and impulses. 'And the public certainly is not served by the continued brain drain of DOJ — we are losing the best among us every day.' Bondi's move came the same day that she celebrated a Supreme Court ruling that decided that individual judges lack the power to issue nationwide injunctions - a historic ruling in a case about the right to birthright citizenship. The ruling was seen as a big victory for Trump as it allows his executive order halting birthright citizenship for children of undocumented immigrants to take effect in states and jurisdictions that did not directly challenge his action in court. It could mean citizenship rules vary from state to state, pending ongoing litigation. The court ruled 6-3 in favor of Trump, with all six conservative justices - including the three he appointed - siding with the president. Speaking at the White House, Trump said: 'This was a big one. Amazing decision, one we're very happy about. This really brings back the Constitution. This is what it's all about.' Bondi joined Trump on stage to mark the victory, saying that the ruling meant 'not one district court judge can think they're an emperor over this administration and his executive powers, and why the people of the United States elected him.'
Daily Mail
3 hours ago
- Entertainment
- Daily Mail
Megyn Kelly parodies Michelle Obama as she hits out at former first lady for 'never having a positive word to say'
Megyn Kelly has hit out at Michelle Obama with claims she 'never has a positive word to say' as the former first lady ventures further into the podcast circuit. With her years in the White House behind her, Michelle has revealed a new side to herself by pivoting into the podcast game with a show co-hosted alongside her brother, Craig Robinson - but Megyn is yet to be impressed. While speaking with the hosts of the Ruthless podcast, Megyn shared a clip of herself and Daily Mail columnist Maureen Callahan spoofing a series of Michelle's 'constantly negative' comments. Before showcasing the clip, the journalist joked that she's been getting into the 'parody business,' with 'targets' including Meghan Markle, the women who participated in the Blue Origin space flight, and now the former Democratic first lady. 'Michelle - she should change her name to Misery Obama. That's really what I think of when I [think of her]. Misery Obama never has a positive word to say. Never. Not about children, not about family, certainly not about her husband,' Megyn said, before mimicking some of Michelle's most talked-about comments. In a skit, the conservative commentator played a character named 'Megyn O,' and took aim at Michelle's comments about how expensive it is to live in the White House. 'We made it through. We got out alive. But what happened to me? What happened to me?' Megyn O joked. Megyn said her new nickname for the former first lady was 'Misery Obama' because of her comments on living in the White House and being a wife 'No one talks about it,' Maureen responded, pretending to be 'Megyn O's' sister in an attempt to impersonate Michelle's brother Craig. The two also poked fun at Michelle for remarks she made detailing the difficulties of having kids and marriage. 'We had so much fun doing this,' Megyn told podcast hosts Josh Holmes, Michael Duncan, and Josh Ashbrook. 'Basically - we're doing the things that Saturday Night Live should do. We're targeting the people who should be subjected to scorn and ridicule, but the left won't touch it because they're too revered,' she added. 'We've been having such a good time just saying what's obvious,' Megyn said. Megyn also took aim at Michelle's shocking comments about Barack on a recent episode of IMO with Michelle Obama and Craig Robinson. When asked if she had ever wanted a son, Michelle revealed, 'I'm so glad I didn't have a boy, because he would've been a Barack Obama.' Her guest contested that a 'baby Barack' would be 'amazing,' but Michelle quickly disagreed, 'No, I would have felt for him.' Craig then cut in and joked, 'She just borrowed our boys,' referencing Michelle's nephews. Megyn has been a longtime critic of the Obamas and has frequently gone after the former first lady on her podcast. She previously blasted Michelle for comments she made about the harsh realities of marriage. During an episode of IMO, Michelle opened up about the struggles she had in her marriage, revealing that she had a 'bad decade' with Barack. 'I tell people - and folks think this is harsh - it's, like "You're gonna have a bad decade,"' Michelle said. 'I mean, I've been married to my husband for 30-plus years... If the odds were you're going to be married to your partner for 50 years and 10 of those years could be bad, you'd sign up for it. You know, and that's really how it works out.' Megyn referenced the clip on one of her episodes in April, staunchly disagreeing with Michelle's take. She explained that during her 17-year marriage with Douglas Brunt, 'not one was bad.' Michelle's latest attempt to tame the rumor mill has only further fueled speculation that her marriage to Barack is on the rocks. The former first lady addressed the swirling divorce rumors head on in an interview with Rachel Martin, host of NPR's Wild Card podcast, released Thursday. But instead of dismissing the rumors altogether, Michelle deflected and instead left fans wondering if the famous couple really do have something to hide. 'The fact that people don't see me going out on a date with my husband sparks rumors of the end of our marriage,' she told Martin, who jokingly claimed the behavior was the 'apocalypse'. 'It's the apocalypse,' Michelle, 61, echoed, before offering up a rather lackluster excuse: 'We don't take selfies.' 'It's like, "OK, so we don't Instagram every minute of our lives." We are 60. We're 60, y'all. You just are not gonna know what we're doing every minute of the day.' Rumors that the couple's 33-year marriage had unraveled began circulating after Michelle was noticeably absent from several high-profile events earlier this year; including the presidential inauguration and funeral of former President Jimmy Carter. They were further exacerbated last week when Michelle was spotted having lunch with her daughters and another, somewhat surprising companion at an exclusive beach club in Mallorca. Barack, however, was noticeably absent.
