Latest news with #erectiledysfunction
Daily Telegraph
12 hours ago
- Business
- Daily Telegraph
LTR Pharma completes ED study milestone
Don't miss out on the headlines from Stockhead. Followed categories will be added to My News. LTR Pharma & co-development partner Aptar Pharma complete extractables study on SPONTAN All identified compounds below ICH safety thresholds for nasal spray-mist erectile dysfunction treatment Leachables study initiated to support FDA regulatory submission under real-world storage conditions Special Report: LTR Pharma has completed a key extractables study for its SPONTAN intranasal spray for erectile dysfunction and kicked off a leachables study as part of a regulatory development program. LTR Pharma (ASX:LTP) said the extractables study, conducted under the supervision of co-development partner Aptar Pharma, evaluated the bottle and pump components of SPONTAN's container closure system. The study confirmed that all detected compounds were below ICH safety thresholds – the internationally recognised standards adopted by the US Food and Drug Administration (FDA) and regulatory authorities worldwide for pharmaceutical impurities. LTR Pharma said the identified compounds would be monitored in the ongoing leachables study. FDA requires extractables and leachables (E&L) studies for all pharmaceutical products to ensure packaging materials do not compromise product safety or efficacy. For nasal spray products, these studies must meet specific regulatory thresholds due to direct tissue exposure. Leachables study now underway The leachables study has started under Aptar Pharma's management, evaluating the potential migration of the compounds from packaging into SPONTAN under real-world storage conditions. LTR Pharma said SPONTAN used industry-standard bottle and pump components as used in multiple FDA-approved nasal spray products. The study will run for at least 24 months to support shelf-life requirements. Consistent with FDA practice for nasal sprays, the company can submit its application once sufficient robust data is available, with study completion continuing post-approval as standard. E&L studies form part of LTR Pharma's comprehensive regulatory strategy following its FDA pre-IND meeting, where the FDA confirmed the proposed development pathway. The company said E&L data were required for the chemistry, manufacturing and controls (CMC) section of its planned new drug application (NDA). With extractables results meeting regulatory requirements, the company progresses to the leachables phase for comprehensive regulatory submission data. Watch: LTR's new appointment Progress on SPONTAN and new US-targeted ROXUS LTR Pharma continues to progress SPONTAN through established regulatory pathways while building commercial foundations through its Australian early access programs. It is also progressing its new ED nasal spray called ROXUS, which offers a fast-track pathway to serve patients through the US personalised healthcare sector. As with SPONTAN, ROXUS is based on the common active ingredient vardenafil. It will be delivered via the 503(a)-compounding pharmacy pathway, which exempts drugs from the usual approval, labelling and manufacturing requirements. "The completion of our extractables study and commencement of the leachables phase keep our regulatory program on schedule,' LTR Pharma executive chairman Lee Rodne said. 'Working with Aptar Pharma provides us with their established expertise in nasal spray device development and FDA submissions. 'These studies are necessary steps in our development pathway, and we look forward to progressing through each regulatory milestone." This article was developed in collaboration with LTR Pharma, a Stockhead advertiser at the time of publishing. This article does not constitute financial product advice. You should consider obtaining independent advice before making any financial decisions. Originally published as LTR Pharma completes study milestone for SPONTAN ED treatment
The Sun
21 hours ago
- Health
- The Sun
Penis pump and Viagra prescriptions soar as NHS spends over £20MILLION helping blokes with erectile dysfunction
The NHS said erection problems are 'very common' in men over 40 BIG RISE Penis pump and Viagra prescriptions soar as NHS spends over £20MILLION helping blokes with erectile dysfunction DOCTORS prescribed a record number of bedroom aids for blokes such as penis pumps and Viagra last year, figures show. The NHS in England alone spent more than £20million helping men dealing with erectile dysfunction. Advertisement 1 Doctors prescribed a record number of bedroom aids for blokes such as penis pumps and Viagra last year Credit: Alamy A total of 24,231 erection devices, including vacuum pumps — as seen in 1997 comedy Austin Powers: International Man of Mystery — and constriction rings were prescribed in 2024/25, the NHS Business Services Authority revealed. That was up by 10,000 on a decade ago. And the £2.8million cost has doubled since 2015. Meanwhile, prescriptions for drugs such as Viagra and Cialis reached 4.7million — up 100,000 on the year before — with a cost of £17.6million. Advertisement The NHS said erection problems are 'very common' in men over 40 and become more likely with age and illness. A spokesman added: 'Effective erectile dysfunction treatment is important for both sexual and mental well-being.' Dr Leyla Hannbeck, chief of the Independent Pharmacies Association, said the pumps were a useful option for people who cannot be prescribed Viagra. She said: 'Viagra and Cialis interact with medicines used to treat angina and certain blood pressure medicines so alternatives are available, including pumps, where taking them is unsuitable.' Advertisement The findings come days after actress Dame Emma Thompson suggested sex should be prescribed on the NHS. She spoke out at a a screening of her 2022 film Good Luck To You, Leo Grande — in which she plays a widow who hires a sex worker. Bionic willies on the rise as more than 500 men with severe erectile dysfunction have £8,000 NHS operation Dame Emma, 66, said: 'You need sex because it's part of our health plan, if you like. 'It should really be on the NHS. Advertisement 'It's so good for you.' Unlock even more award-winning articles as The Sun launches brand new membership programme - Sun Club.
Telegraph
4 days ago
- Health
- Telegraph
Interpol seizes erectile dysfunction and anti-anxiety medication
Erectile dysfunction and anti-anxiety medication were among the most common illegal pharmaceuticals seized by Interpol in a cluster of raids spanning 90 countries. Investigators retrieved £47 million worth of counterfeit or illegal medication as part of an operation codenamed Pangea XVII. From December 2024 to May, police arrested 769 suspected drug traffickers and dismantled 123 criminal gangs. Psychostimulants, anti-anxiety drugs and medications for Parkinson's disease topped the list as the most seized product type. Erectile dysfunction medicines were the second highest. In Britain, drugs seized included painkillers, antidepressants and sleeping pills. Australia recorded the largest seizures globally, with psychostimulants (drugs used to treat sleepiness) modafinil and armodafinil being the most common. This was followed by anti-smoking nicotine pouches and erectile dysfunction medicines. Ozempic -style weight loss drugs, such as semaglutide, and peptides used for bodybuilding and cosmetic enhancements were also seized in huge quantities. The ease of purchasing these drugs either via social media or from online marketplaces are making them rapidly grow in popularity. A single semaglutide pen may sell for several hundred US dollars on the black market, Interpol said. About 13,000 criminal-linked websites, social media pages, channels and bots used to market and sell illegal or falsified medicines have been shut down Criminal networks now view these drugs as 'lucrative and relatively low-risk opportunities' for selling poor quality or counterfeit products. Law enforcement agencies launched 1,728 investigations and issued 847 search warrants targeting criminal networks. Some 93 per cent of the illicit pharmaceuticals seized lacked regulatory approvals from national health authorities. The remaining 7 per cent were confirmed as either counterfeit, diverted, or misbranded products. Malaysia removed the greatest number of online listings (7,000), followed by Russia, Ireland, Singapore and Iran. The five countries collectively accounted for 96 per cent of all listings taken down. In Burkina Faso, 816,000 tablets including analgesics and anti-inflammatories were discovered hidden in vehicles. Mexican authorities intercepted benzodiazepine drugs including 27,000 clonazepam tablets and 20,000 alprazolam tablets passing through a courier facility in Tijuana. In Portugal, anabolic steroids were discovered in eight prisons across the country, unveiling evidence of a criminal network smuggling illicit substances into correctional facilities. 'Serious risk to public health' David Caunter, director pro tempore of organised and emerging crime at Interpol, said: 'Fake and unapproved medications are a serious risk to public health. They can include dangerous or illegal ingredients potentially resulting in severe illness, or even death 'The rapid growth of online platforms has made it easier for these unsafe drugs to reach people as well as opening new opportunities for criminal networks to exploit. 'Working together through Operation Pangea, countries are taking action to protect people's health and keep healthcare systems safe.'
Daily Mail
6 days ago
- Entertainment
- Daily Mail
Beau Ryan makes SHOCK Viagra confession live on air: 'I can't even describe it'
Beau Ryan has made a shock confession about a less-than-stellar experience with erectile dysfunction medication. The TV and radio star, 40, revealed on his Triple M Breakfast show Beau, Cat & Woodsy on Wednesday, that he got a little more than he bargained for when sampling a pill gifted by a friend. He revealed to co-hosts Aaron Woods and Cat Lynch his ordeal began after receiving the unique gift at his recent 40th birthday bash. 'On my 40th birthday a couple of weeks ago, my mates gave us presents, but one of my close mates, as a joke, he popped a Cialis in my pocket, which is like Viagra for those that don't know,' the former rugby league star admitted. He went on to explain he had completely forgotten about the little pill until discovering it in his jacket after arriving home last Friday night. From A-list scandals and red carpet mishaps to exclusive pictures and viral moments, subscribe to the DailyMail's new showbiz newsletter to stay in the loop. He told his wife Kara about the unexpected gift, and the intrigued couple began to research its properties. 'I said to my wife Kara, "I've got one of these Cialis",' he said. 'We started googling it and looking into it and I said, "I should take it".' 'So, I had it. I was like, "Let's just ride this out and see what happens".' Beau went on to reveal that after popping the pill, he waited on his bed in anticipation for the pill to work its magic - but was left disappointed. 'The first hour I was laying there I was really excited, but I was so tired from the week that I was still trying to get myself up and excited for it,' he said, before admitting he promptly put a movie on and fell asleep. The ordeal didn't end there, with Beau then revealing it all came to a head when he woke the following morning. 'I wake up around 6am to go to the bathroom and get ready for Saturday. I've got my son's footy and soccer, my daughter's soccer, and I've got a pitched tent like you wouldn't believe,' Beau candidly admitted. 'I can't even describe it. It couldn't be more pitched,' he added. Beau went on to reveal that after popping the pill, he waited on his bed in anticipation for the pill to work its magic - but was left disappointed A shocked Cat asked Beau if he was able to 'take care of it and then it stops?'. The footy star admitted that nothing he could do would allay the effects of the pill. To make matters worse, Beau went on to explain that the pill continued to work its magic for an entire day of sporting activities with children Remi, 11, and Jesse, seven. 'Not only was I pitching a tent at soccer, we had photos for the footy afterwards at 10am and I'm pitching a tent still,' he continued. 'Then, my son plays footy just before midday, the tent is still up. Then my daughter's soccer game is in the afternoon - the tent is still well and truly up.' Beau said he was still feeling the side effects from the pill when he finally arrived home that afternoon, but was unable to take advantage. 'Finally, I come in and have a shower and literally on cue as Kara walks in the door the tent comes down,' he said. 'It was the first window in my week where Kara said, "the kids are busy out there let's lock the door".' Beau recently revealed the reason behind his shock exit from I'm A me Out Of Here! Australia in 2022. Speaking on air in January, Beau said his stint on the Channel Ten show was filmed during Covid lockdowns and left him feeling exhausted. 'Watching the new season of IAC last night, brought back a lot of memories. It was a Covid series and about a month before I agreed to go on the jungle, we were meant to go on The Amazing Race for a season so I'd done quarantine,' Beau began. 'Then it was deemed too dangerous to continue the series. I was 12 days in to quarantine, came out and agreed to do the jungle... two more weeks of quarantine!' Beau said the consecutive stints in isolation took a toll on both his mental and physical wellbeing and he was not in a good place when he began his stint on IAC. 'I was so mentally cooked and physically drained. I just had to get home. I was concerned about my wife who was home-schooling the kids,' he continued. 'My wife was alone with the kids, no access to family. I'm not making any excuses, I carried on like a pork chop.' The presenter added that while he regretted leaving the show under such circumstances he had to do what was right for his family. In 2022, in what was I'm a Celebrity's eighth season, Beau walked out on the 14th day in the jungle - which cost him $200,000.
Daily Mail
23-06-2025
- Health
- Daily Mail
Revealed: Areas in England most likely to use Viagra... do YOU live in one of them?
Men in Yorkshire are the most likely in England to need a bit of assistance in the bedroom, NHS data suggests. Official data shows just over nearly 3.6 per cent of men in the East Riding were prescribed an erectile dysfunction medication like Viagra, in 2024. This was followed by men in Northumberland and Dorset who came second and third for taking such drugs, at 3.4 and 3.3 per cent respectively. The north and north-east of England appears to be particularly hard-hit by impotency with many of its cities and towns featuring in the top 10 areas for such prescriptions. On the opposite end of the spectrum, men in Leicester City appeared to be the least likely to need help from the little blue pill to maintain an erection, with only 1.5 per cent taking them. Other areas In England with low similarly low prescription rates were North West London (1.7 per cent) as well as Cambridgeshire and Peterborough (1.9 per cent). For comparison, 2.4 per cent of men across all of England were prescribed an erectile dysfunction medication last year. These figures were calculated by examining NHS prescription data collected from England's 106 Clinical Commissioning Groups. In total, last year almost 770,000 men in England got nearly £5million prescriptions for the drugs, costing the NHS just under £17million. However, the data might not give a true indication of where men are most reliant on the little blue pill. Men can buy a course of drugs like sildenafil—the generic version of Viagra—over the counter for as little as £15 with similar tablets also available online for as little as £1.30 per pill. Such private purchases of the drug wouldn't be included in the NHS data. Additionally, while most famous for their libido boosting affects, many of the drugs aren't just prescribed for erectile dysfunction. Such medications also teat pulmonary hypertension, a type of high blood pressure in the arteries that supply the lungs. The same mechanism by which the drugs increase blood flow to the penis also relaxes blood vessels in the chest helping to alleviate this condition. Medics have also previously suggested that the data may not solely reflect where the drugs are needed the most by men, but also where they feel the most comfortable taking to their GP about sexual health. Impotency is no laughing matter and men suffering from the problem frequently are urged to seek advice from their GP. Not only can the problem impact their sexual and mental health, erection problems can also be potential sign of serious health problems like cardiovascular disease. However, not all men are advised to take drugs like sildenafil, for example those with heart problems are warned against taking it. About one in 100 people taking sildenafil will experience common side effects from taking sildenafil. These include headaches, nausea, hot flushes, indigestion, a stuffy nose and dizziness, according to the NHS. Those taking the pills for longer periods, such as for pulmonary hypertension, are more likely to experience these effects than those taking the pills on an 'as needed' basis for erectile dysfunction, the health service says. More serious side effects requiring urgent medical care are estimated to affect less than one in 1,000 people. These include seizures, suffering a prolonged and potentially painful erection especially for over two hours, chest pain, and in very rare cases a life-threatening allergic reaction to the medication called anaphylaxis. Last year MailOnline revealed that popular erection pills such as Viagra have been linked to more than 200 deaths in Britain. None of the fatalities—all of which have occurred since 1998—are proven to have been caused directly by the drugs. Erectile dysfunction, sometimes shortened to 'ED' is thought to effect about half of men over 40. While most cases are isolated and nothing to worry about, repeated or sustained impotency should be checked out by a GP.
