'Irrational' fixed dose combos harmful, may face ban: Expert panel
fixed dose combinations
(FDCs) found they may pose a risk to human beings. Considering that they are "irrational," the experts have recommended their prohibition.
There are about 16 odd FDCs including Aloe Vera+Jojoba oil+Vitamin E, Aloe Vera+Orange Oil, Aloe Vera+Vitamin E+Herbal, Aloe Vera+Jojoba Oil+wheat germ oil+Tea Tree oil, among others, which are likely to be part of a list of products to be banned. The other FDCs which fall under the same category are Paracetamol + Lidocaine, acetyl salicylic acid+ethoheptazine used as pain relievers. They have been under the government scanner from 2021.
A FDC contains two or more active ingredients in a fixed dose ratio, but in India several FDCs are found to be irrational or are not scientifically validated for safety or efficacy through rigorous tests for patients.
by Taboola
by Taboola
Sponsored Links
Sponsored Links
Promoted Links
Promoted Links
You May Like
New Container Houses Vietnam (Prices May Surprise You)
Container House | Search Ads
Search Now
Undo
Earlier in March 2023, companies producing such FDCs were asked to give a presentation, representing their case justifying the need for these products. The companies were asked to submit a summary with the "highest level of evidence," supporting the claim of postulated advantage/rationale, along with the published data regarding safety and efficacy of FDC. They were asked to share whether these FDCs are marketed in the EU, UK, Canada, Australia, Japan and the US.
The companies were also told to mention country wise product names, ingredients, dosage forms, it's strength, amount of usual ingredients per dosage form and the countries where the drug is marketed, approved, withdrawn, among other details.
Live Events
"The companies were heard out and it was found that "there is no therapeutic justification" for these FDCs, and they may involve "risk" to human beings," said a senior government official.
"Hence, in the larger public interest, it is necessary to prohibit the manufacture, sale or distribution of this FDC", another person said.
They were earlier considered as "irrational" by a panel led by Chandrakant Kokate, vice-chancellor of KLE University in Karnataka. However, a sub-committee formed under the chairmanship of Nilima Kshirsagar, former dean of G.S. Medical College and KEM Hospital in Mumbai, was asked to examine and review the safety, efficacy and therapeutic justification of these drugs.
The sub-committee recommended "prohibition" of these FDCs, saying they could pose a risk to human beings.
Last month the report was submitted before India's top technical body on drugs which agreed with the recommendations of the subcommittee. "The recommendations have now been sent to the health ministry for further action," added the government official.
In India, the overall market for aloe vera combination is worth ₹90. 7 core and growing at 27% annually, PharmaTrac data shows.
Hashtags
Try Our AI Features
Explore what Daily8 AI can do for you:
Comments
No comments yet...
Related Articles
Time of India
31 minutes ago
- Time of India
6 Lesser known reasons to add raw papaya to your diet
Often skipped for its ripe version, raw papaya is great for digestion and detox. It has digestive enzymes and lots of fiber that help clean your system and boost metabolism. Cook it into a dry sabzi with mustard seeds and curry leaves, or add it to salads and soups for a fresh bite that keeps you going. In India, raw papaya is mostly relished as a sabzi or as a healthy addition to lentils, but in several Asian and Oriental cuisines raw papaya is enjoyed raw or partially cooked in the form of salads, soups or even pickles. Well, if you too are intrigued to try raw papaya in the form of a nice spicy yet healthy salad? Then read on to follow us through a simple recipe of raw papaya and reasons why you should add this super healthy vegetable to your daily diet. What makes raw papaya so healthy? Raw papaya is naturally loaded with essential nutrients like vitamins A and C, which helps support immune functioning and skin health. Moreover, the presence of folate and potassium in this vegetable make it great for balancing electrolyte levels in the body. In fact, the presence of papain, a digestive enzyme in raw papaya aids in breaking down proteins, helps in promoting better digestion and ensures regular bowel movements. This is because of its high fiber content that contributes to a healthy weight management by providing satiety. Raw papaya also boasts anti-inflammatory properties due to its antioxidant compounds, which can help reduce the risk of chronic diseases and promote overall are some more reasons to add raw papaya to the daily diet. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Use an AI Writing Tool That Actually Understands Your Voice Grammarly Install Now Undo In most Indian households raw papaya is mostly consumed in the form of a vegetable, but little do we know that this humble vegetable can also be consumed in the form of a juice to reap maximum benefits of this vegetable. Here's all you need to know about raw papaya and how its juice can help boost metabolic health and immunity. Supports Digestive Health Raw papaya contains a digestive enzyme called papain, which aids in breaking down proteins and can improve digestion. In fact, the fiber content in the salad promotes regular bowel movements and supports a healthy gut. A diet rich in fiber can prevent constipation and support overall digestive health. Promotes Weight Management Planning to lose weight? Then raw papaya salad is an excellent choice. It is low in calories and high in fiber, which can help you feel fuller for longer. The salad's crisp texture and subtle flavors can satisfy cravings without adding excessive calories to the daily diet. Including raw papaya salad as a side dish or a light meal can support your weight management goals. Anti-Inflammatory Properties Raw papaya contains several compounds with anti-inflammatory properties. These include antioxidants like vitamin C and flavonoids, which can help reduce inflammation in the body. Chronic inflammation is linked to various health issues, including heart disease and arthritis. Regularly consuming raw papaya salad may help combat inflammation and promote overall health. Improves Skin Health The nutrients in raw papaya contribute to healthier skin. Vitamin C plays a crucial role in collagen production, which helps maintain skin elasticity and prevents premature aging. The antioxidants in papaya also help combat oxidative stress, which can lead to skin damage. Adding raw papaya salad to your diet can promote a radiant complexion and overall skin health. Versatile and Delicious The best thing about this vegetable is that it can be used in so many interesting ways to create delightful delicacies. In fact, raw papaya salad tastes best when paired with protein, nuts and unique spices. So, if you too are bored of eating raw papaya in the same old way, then follow us through this easy recipe and enjoy. How to make Raw Papaya salad at home Here's a simple recipe for making Som Tam, the delicious Thai raw papaya salad: Ingredients 1 medium green papaya, 1-2 medium tomatoes, 1 carrot, 2-3 green beans, 2-3 tablespoons fish sauce, 1-2 tablespoons lime juice, 1 tablespoon palm sugar 2-3 Thai bird's eye chilies/ Indian green chilies, 2-3 tablespoons roasted peanuts, coriander or mint leaves Step 1 To begin with this easy recipe, wash and cut the papaya, then using a grater or a food processor, shred the green papaya into thin strips. You can also use a julienne peeler if available. In a small bowl, combine the fish sauce, lime juice, and palm sugar. Stir until the sugar dissolves. Step 2 Now take a mortar and pestle and lightly pound the chilies and some of the peanuts to release their flavors. Be careful not to over-mash; you want some texture. A liver-healthy diet focuses on whole foods like fruits, vegetables, whole grains, lean proteins, and healthy fats. Also, limit processed foods, added sugars, and alcohol. Staying hydrated and including liver-friendly nutrients like antioxidants, fiber, and omega-3 fatty acids can support detoxification and overall liver function. Step 3 In a large bowl, combine the shredded papaya, chopped tomatoes, shredded carrot, and green the dressing over the vegetable mixture and toss everything together well. Adjust seasoning if needed, adding more fish sauce, lime juice, or sugar to taste. Step4 Transfer to a serving plate and sprinkle with the crushed peanuts and fresh herbs. Serve immediately, preferably with sticky rice or as a side dish. Get the latest lifestyle updates on Times of India, along with Friendship Day wishes , messages and quotes !
Time of India
an hour ago
- Time of India
The puberty talk: When to talk, what to talk, and the challenges, according to experts
A recent poll highlights the challenges parents face when discussing puberty with their children, revealing varied approaches and anxieties. Many parents are unsure about the right age to begin the conversation, with some feeling embarrassed or ill-equipped. Experts recommend starting early, being proactive, and utilizing resources to guide children through physical and emotional changes. Talking to kids about puberty is important. But when and how to start the conversation is a grey area for many parents. A new poll has looked deep into the challenges parents face about having 'the puberty talk' with their children. When to start the conversation According to the University of Michigan Health C.S. Mott Children's Hospital National Poll on Children's Health, some of the common challenges that parents face are: choosing the right age to talk about the changes in their children's bodies, and also sex education. The poll found that parents are equally split in thinking it's best to start talking about puberty before age 10, at age 10, or when children are older. 'It's easy to assume a child is too young for conversations about puberty, but many parents are surprised to find their tween already showing signs of puberty or asking unexpected questions about body changes. Starting the conversation early gives parents a chance to shape the message in an age-appropriate way and help kids know what to expect, so they're not confused or anxious. If parents don't open the door to these talks, kids may get their information elsewhere, like from classmates, social media, or what they see on TV,' Mott Poll Co-Director Sarah Clark, M.P.H. , said, in a statement. The polls also found the kinds of approaches, worries, and gaps parents have in their tweens for this major stage of development. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Buy Resmed AirSense 11 with flat 20% off ResMed Buy Now Undo About half of the parents said their approach to the puberty talk was 'proactive'. Two in five had the conversation only when asked. Surprisingly, 5% of the parents avoided the conversation altogether. One in five parents was worried about feeling embarrassed about having the conversation. One in six said they were anxious about saying the wrong thing. Among parents of children aged 10-12, a quarter said their child didn't want to talk about puberty. Parents of those aged 7-9, nearly a third, believed the kids were too young to understand. What to talk During the puberty talk, nearly half of the parents shared their puberty experiences with their children. Less than one-third of the parents shared that they have had the puberty conversation with their children. However, more than a third of the parents revealed that their parents never had this conversation with them. 'Whether they realize it or not, parents may bring their own experiences into their parenting approach. Many parents said they had little or no discussion of puberty when they were young. If puberty was treated as an awkward or embarrassing subject growing up, that can make it harder to know how to begin,' Clark said. How much to talk about puberty Source: CS Mott Children's Hospital National Poll an Children's Health, 2025 The poll revealed that parents have some common challenges, such as whether, when, and how much to talk about sex and reproduction. 'Early conversations should focus on making kids aware that they will experience physical and emotional changes , and reassuring them that those changes are normal. Discussions about sex can occur over time,' Clark said. Clark also recommended that parents look for resources such as parenting books on how to talk to kids. Annual check-ups may also be a good opportunity for both parents and children to learn about puberty-related changes and ask the doctor questions. Recognizing puberty signs The poll revealed that about half of the parents were confident that they could recognise signs of puberty in their children. 60% of parents of children aged 10-12, and 17% parents of children aged 7-9 were able to notice these changes. However, fewer than a third of parents weren't sure what changes to look for. No more guesswork: Doctor busts common myths about women's health Some parents said that their children asked about their bodies, their parents' bodies, or other puberty-related topics. Clark added that parents should be open to discussing when such moments arise. For instance, when the child asks questions about puberty. 'Puberty isn't just about physical changes — it's also a time of emotional disruption, which can make open communication challenging. Many tweens feel embarrassed or uncomfortable talking with their parents about these changes. To help ease the discomfort, some parents may give their child an age-appropriate book or video about puberty and allow the child to explore the topic privately. Often, that leads to additional discussion with parents,' Clark added. Get the latest lifestyle updates on Times of India, along with Friendship Day wishes , messages and quotes !
Time of India
2 hours ago
- Time of India
Weekly Health Horoscope Predictions, August 03 to August 09, 2025: Tips for wellness and balance based on each zodiac sign
Aries All your aches and pains seem to vanish, giving you a fresh burst of energy. Your dedication to exercise and health routines is finally paying off. An ailment you've been suffering from shows signs of recovery. You may feel more alert, mentally at ease, and ready to engage in physical activities. A home remedy or advice followed recently appears to be effective. If you've been considering a new fitness regime, now is the perfect time. Your body responds well to the changes you're making—especially in diet and exercise. This could mark the beginning of a lasting healthy lifestyle. Keep it up! Taurus Health remains stable, and those who have recently adopted a new routine will begin to see positive effects. If you've been trying to get back in shape, your efforts are likely to succeed. You may become more conscious of your image and physical appearance. Minor ailments are under control, and you're likely to feel more energized throughout the day. Following health advice and sticking to a routine will help you stay fit. It's a good time to cut down on junk food and incorporate more physical activity. Continued focus on wellness will bring visible results—just stay disciplined and consistent. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Buy Resmed AirSense 11 with flat 20% off ResMed Buy Now Undo Gemini Your health is in good shape, and you may feel more motivated than ever to improve your lifestyle. A friend's encouragement might inspire you to adopt healthier habits. Listening to wellness advice proves beneficial, especially if you've been planning to exercise or eat better. Those trying to get fit will start seeing progress. It's a good time to avoid late nights, especially if you're driving or have early commitments. Your active approach to health is commendable and will yield long-term results. Keep up the discipline—your physical and mental well-being are aligned right now. Cancer You're in a good health phase, thanks to your disciplined lifestyle. Healthy dietary habits are keeping you energetic and alert. Following a set routine brings mental peace and helps manage stress effectively. Adhering to your schedule—whether exercise, sleep, or meals—keeps both your mind and body balanced. Some of you might consider attending a religious or spiritual gathering, which will further boost your emotional well-being. If you've been recovering from a minor illness, expect steady improvement. Avoid outside food for now, as your body may be sensitive. Continue this momentum—your efforts are showing long-lasting benefits. Leo Your focus on fitness is finally yielding results. Some of you may rediscover the joy of exercising or take up a new physical activity that excites you. A home remedy may work wonders, steering you toward better health. Your energy levels remain high, but don't neglect small health issues—especially digestive concerns caused by poor diet or stress. Eating right and staying active are your best tools now. If you've been under the weather, signs of recovery are strong. The stars support your efforts to maintain overall well-being. Continue positive thinking, and you'll notice a significant boost in physical and mental health. Virgo Your health is in excellent shape, thanks to your consistent efforts. You're taking all the right precautions and following a disciplined routine. Exercise and a focus on diet are helping you stay fit and feel good. Junk food may tempt you, but you know better—resisting it now will pay off. Minor lifestyle improvements are bringing major benefits, both physically and mentally. If you've been struggling with a recurring issue, this is when things start improving. Avoid overexertion, but do stay active. Mental peace also improves, as your wellness routine brings clarity and confidence. Keep it going! Libra Your health remains steady, but now is a great time to focus more on emotional balance. While physically you may feel fine, stress could sneak in due to work or personal responsibilities. Meditation, walking, or light stretching will help calm your mind. Listen to your body's subtle signs and don't ignore fatigue or irregular sleep. Some of you might benefit from changing your diet—more hydration and natural foods will do wonders. Avoid overindulgence, especially in rich or processed foods. A balanced lifestyle will bring both mental clarity and physical energy. Small daily practices will make a long-term difference. Scorpio Your energy levels are fluctuating, so it's essential to strike a balance between rest and activity. Overworking may lead to fatigue or stress-related issues. Pay attention to your body—if it signals a need to slow down, listen. Incorporating yoga, breathing exercises, or a simple walk outdoors can recharge you. Some of you may face minor digestion or sleep troubles, which can be managed through a better routine and clean eating. Emotional stability is key—talking to a close friend or journaling may help release mental clutter. Stay hydrated and avoid stimulants late at night. Health improves with conscious daily effort. Sagittarius Your vitality is high, and this is a great time to get back into a fitness routine—or build one if you haven't already. Outdoor activities, hiking, or nature walks will do wonders for both your body and mind. However, avoid recklessness—overexertion or ignoring body signals could lead to minor injuries or fatigue. Try to balance your adventurous spirit with mindfulness. If you've been facing stress, creative outlets like art, music, or journaling may help bring emotional release. Prioritize hydration and a consistent sleep schedule. Your physical health thrives when you're mentally centered—maintain that alignment for overall well-being. Capricorn Your disciplined mindset benefits your health now. You're likely sticking to a consistent routine, which supports both physical and mental wellness. However, you may feel occasional stiffness, fatigue, or stress from work pressure—don't ignore it. Focus on posture, hydration, and taking regular breaks, especially if you have a desk job. Gentle exercises like stretching, walking, or swimming will help ease any tension. Emotional balance is equally important—talk to someone or unwind with calming music or meditation. Avoid skipping meals or sleep due to work overload. With a little mindfulness, you'll maintain both strength and stamina through the week. Aquarius Your mental energy is high, but your body may need extra care. You may be juggling too many things at once, leading to stress or tension headaches. Prioritize rest and try not to overthink. Mind-body balance is key right now—meditation, journaling, or even quiet walks can help bring clarity. Avoid screens late at night and get enough sleep to support your overall health. You might benefit from light cardio or a new wellness routine that includes creativity and flexibility. Keep an eye on hydration and dietary habits—small improvements go a long way. Emotional balance will uplift your physical state. Pisces You're entering a phase of emotional healing, and your body responds well to inner peace. Focus on calming practices—yoga, meditation, or time near water can help you restore balance. Fatigue may surface if you've been overextending yourself emotionally or mentally. Listen to your body and take rest when needed. Avoid sugar overload or emotional eating, as your sensitivity is heightened. Creative outlets like painting, music, or dance will also serve as powerful healing tools. This is a good week to reset your sleep cycle and simplify your wellness habits. Prioritize mental clarity and gentle self-care—it will uplift your overall vitality. Discover everything about astrology at Times of India , including daily horoscopes for Aries , Taurus , Gemini , Cancer , Leo , Virgo , Libra , Scorpio , Sagittarius , Capricorn , Aquarius , and Pisces . Read your detailed Horoscope Today and Horoscope Tomorrow here.
