
Robert Jarvik, 79, dies; a designer of the first permanent artificial heart
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During the seven-hour surgery, according to the retrospective, Clark's heart muscle tore like tissue paper as it was removed after so many years of being treated with steroids.
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Upon awakening, DeVries said, Clark told his wife, Una Loy Clark, 'I want to tell you even though I have no heart, I still love you.'
Clark survived for 112 days, attached to a 400-pound air compressor, roughly the size of a dishwasher, that helped the Jarvik-7 pump blood through his body. But he never left the hospital, and he experienced seizures, kidney failure, and a broken valve on the heart that needed replacing.
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DeVries said in 2012 that Clark had probably received too many antibiotics, which can make it more difficult to fight off infections. He died March 23, 1983, from complications related to a bacterial infection of the colon.
William J. Schroeder, 52, a retired federal worker who was the second patient to receive the experimental Jarvik-7 artificial heart, lived for 620 days before dying in 1986. Another early recipient of the Jarvik-7, Murray P. Haydon, lived for 488 days before dying at 59.
Their survival demonstrated that people 'could live long term on the plastic and metal device,' The New York Times reported upon Schroeder's death. But the newspaper added that strokes and other complications that recipients suffered 'impaired the quality of their lives and blunted initial enthusiasm for the heart.'
Dozens -- by some accounts hundreds -- of reporters showed up at the University of Utah hospital to cover Clark's surgery. Some celebrated the news, comparing the breakthrough to man's first walk on the moon. Others, however, criticized what they called the 'Frankenstein'-like aspects of the Jarvik-7 and asked whether the medical team was trying to play God by deciding who received the artificial heart.
By the mid-1980s, medical ethicists and theologians were debating whether artificial hearts improved life or extended a painful decline toward death. At a 1985 symposium of religious figures and doctors in Louisville, Ky., a Jesuit theologian noted that in the Christian view, 'life is a basic good but not an absolute good,' adding, 'There is a limit on what we may do to preserve our lives.'
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After five patients received the Jarvik-7 as a permanent artificial heart, Dr. Jarvik said, the device was used hundreds of times as a temporary implant for patients until they could receive a donor heart. One such patient lived 11 years after receiving his donor heart, he said; another lived 14.
In January 1990, the FDA withdrew its approval of the Jarvik-7, citing concerns about the manufacturer's quality control.
In a 1989 interview with Syracuse University Magazine, Dr. Jarvik admitted that his belief the Jarvik-7 was advanced enough to be used widely on a permanent basis was 'probably the biggest mistake I have ever made.'
Still, he defended his work. Of the five recipients of the permanent Jarvik-7, he told the magazine, 'These were people who I view as having had their lives prolonged,' adding that they survived nine months on average when some had been expected to live 'no more than a week.'
'I don't think that kind of thing makes a person in medicine want to stop,' he said. 'It just makes you all the more interested in working it through so it can be better.'
Robert Koffler Jarvik was born May 11, 1946, in Midland, Mich., and grew up in Stamford, Conn. His father, Norman, was a physician with a family practice. His mother, Edythe (Koffler) Jarvik, handled scheduling for the practice and later taught typing.
From an early age, Robert was a tinkerer. As a teenager, he made his own hockey mask and began developing a surgical stapler. He attended Syracuse University from 1964 until 1968, intending to study architecture, but his interest turned to medicine after his father survived an aortic aneurysm, and he received a degree in zoology. Norman Jarvik died in 1976 after a second aneurysm.
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'I knew that my father was going to die of heart disease, and I was trying to make a heart for him,' Robert Jarvik once said. 'I was too late.'
He studied medicine at the University of Bologna in Italy for two years and received a master's degree in occupational biomechanics from New York University before moving to the University of Utah in 1971. He received his medical degree there in 1976, but he did not follow the traditional career path of internship and residency. He was more interested in developing an artificial heart.
Working with Dr. Willem J. Kolff, director of the university's Division of Artificial Organs, Dr. Jarvik designed a series of mechanical hearts. One of them, according to an article in the Times in 1982, was implanted in a cow named Alfred Lord Tennyson, who survived for 268 days, a record for an animal.
In 1985, Dr. Jarvik married Vos Savant, who was listed in Guinness World Records in the 1980s as having the highest recorded IQ (228).
In addition to his wife, Dr. Jarvik leaves his daughter, Kate Jarvik Birch, and his son, Tyler Jarvik, from his marriage to Elaine Levin, whom he married in 1968 and divorced in 1985; Vos Savant's two children, Mary (Younglove) Blinder and Dennis Younglove, from a previous relationship; a sister, Barbara, and a brother, Jonathan; and five grandchildren.
In the late 1980s, his company, Jarvik Heart Inc., began developing smaller, less obtrusive implements, known as ventricular assist devices. Unlike the Jarvik-7, these devices do not replace a diseased heart but assist in pumping blood from the lower chambers of the heart to the rest of the body. One such device, the Jarvik 2000, is about the size of a C battery. A pediatric version, called the Jarvik 2015, is roughly the size of an AA battery.
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According to a 2023 study of the artificial heart market, a descendant of the original Jarvik-7, now owned by another company, is called the SynCardia Total Artificial Heart. It is designed primarily for temporary use in patients who face imminent death while awaiting transplants. The study found that the device had been implanted in more than 1,700 patients worldwide.
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Boston Globe
2 hours ago
- Boston Globe
A brain-injured football player returns home, his life changed forever. His family seeks answers from Sharon officials.
In his largely immobile left hand, he grips a stuffed toy teddy bear — a gift from an ambulance crew that transported him as he lay near death after he suffered a catastrophic brain injury during Sharon's Thanksgiving football game last year. Get Starting Point A guide through the most important stories of the morning, delivered Monday through Friday. Enter Email Sign Up His parents, meanwhile, attend to him around the clock while they and others wait for the Sharon school district to accept its share of responsibility for Rohan's devastating plight. Advertisement Three months have passed School administrators have yet to directly address questions about deficiencies, detailed in the Globe report in May, that may have contributed to Rohan's trauma. After spending more than $10,000 on an external investigation, according to a document obtained by the Globe through a public records request, they have not shared any of the investigative report with Rohan's family and have refused to release it to the public. Advertisement Some of the district's purported failures are powerful reminders to schools across the country about the life-or-death consequences of preventing, preparing for, and responding to medical emergencies in sports. 'No other parent should have to worry that what happened to Rohan will happen again,' said his mother, Deepika Talukdar. The district said in a statement, 'Sharon Public Schools continues to keep Rohan and his family in our thoughts and prayers through his recovery. The district maintains its support for the Shukla family while recognizing that a situation of this nature warrants maintaining their privacy.' Rohan's parents said they appreciate the district helping with Rohan's recovery, including preparing for him to possibly return to school one day. But they continue to seek information in the investigative report and said they have been willing to sacrifice privacy in the interest of student safety. School officials said in response to the Globe's records request that they are withholding the investigative report in part because they consider legal action 'reasonably foreseeable.' Rohan's parents declined to comment on possible litigation. The stakes may be sizable given the severe impact on Rohan and his family. Rohan had never needed medical care for anything but annual physicals before Thanksgiving. Now he needs help to perform his most basic bodily functions. He exists, even at home, as a long-term patient as much as a son and sibling. Advertisement The district's most glaring flaw, as the Globe reported, was perhaps not employing a full-time trainer during the 2024 football season, relying instead on part-timers only on game days, despite complaints from numerous coaches, including the head football coach, about player safety. Amid the lack of coverage, Rohan was permitted to return to play without submitting a medical clearance form or receiving a mandatory cognitive evaluation after he suffered a football concussion four weeks before the Thanksgiving game. He then was involved in a helmet-to-helmet collision in the last practice before Thanksgiving — a potentially dangerous blow that went undetected by the coaches. Rohan Shukla is wheeled by his father, Abhishek, down a newly installed ramp in the backyard of the family home. John Tlumacki/Globe Staff The problems outlined by the Globe have prompted townspeople as prominent as the chair of the Sharon School Committee to assert the district bears some responsibility for Rohan's crisis. Rohan was a sophomore honors student before his education abruptly ended on Thanksgiving. 'I do not believe that what happened to Rohan Shukla wasn't preventable,' the committee chair, Avi Shemtov, said during a candidate forum in May. 'I don't think the blame lies really anywhere other than solely with the school district — that includes the school committee and the administration — for not having a full-time athletic trainer." The unreleased investigative report could possibly include flaws in Rohan's case beyond those previously identified by the Globe. School officials, for example, responded in June to the records request by stating they did not possess a written medical emergency response plan for the high school — an apparent violation of state law. By statute, every district must 'ensure that every school under its jurisdiction has a written emergency response plan that addresses both medical and behavioral health crises to reduce the incidence of life-threatening medical emergencies and behavioral health crises and to promote efficient and appropriate responses to such emergencies.' Advertisement The district, however, asserted Friday in its statement for this story that it does possess written medical emergency response plans for every school in the system. Shemtov, the school committee chair, said the board will seek clarity on the matter. 'After being provided the contradictory statements issued by district administration to the Globe, the school committee is aware of the discrepancy and will be looking into it,' he said. Notable among the additional factors the Globe cited in Rohan's case was the district's decision to replace Sharon High's full-time athletic director before the 2024 season with an administrator who served as both a vice principal and athletic director — a formidable challenge for a school of Sharon's size, with an enrollment of 1,161 and 50 boys' and girls' sports teams. What's more, Sharon officials pitted their low-rated football team against a lineup of punishing opponents. Fourteen Sharon players missed multiple games because of injuries as the team went winless in 11 contests, losing by an average of nearly 40 points. Rohan and five teammates suffered documented concussions. 'It was noncompetitive and unsafe,' head coach Ben Shuffain told the Globe in April. Rohan's parents believed he entered the Thanksgiving game with extra head protection by wearing a shell cover over his helmet that the school had recommended they buy. But the cover wasn't the most protective available, and when the back of Rohan's head crashed to the ground after he made a dazzling defensive play, the shell provided no padding at the point of contact, Shuffain said. Advertisement School officials said in their statement, 'Student health and safety remain the forefront of the district's academic, extracurricular, and athletic initiatives.' Deepika Talukdar exchanges planted kisses with her son, Rohan Shukla, in his makeshift bedroom in the family's dining room. John Tlumacki/Globe Staff Rohan suffered an acute subdural hematoma, a massive brain bleed that with each passing minute reduced his chances of survival. He needed emergency surgery, but vital time was lost, first, because Sharon — unlike many other schools — did not post an ambulance at the Thanksgiving game. Rohan was clinging to life by the time a town ambulance delivered him to Good Samaritan Hospital in Brockton, a lower-level trauma center ill-suited to treat him. He desperately needed an airlift to Massachusetts General Hospital. But MedFlight helicopters were grounded by stormy weather, and Rohan's brain continued bleeding during the wait for a specially equipped ground ambulance. In all, nearly three hours passed between his head hitting the ground and his arrival in an MGH operating room — too long to prevent critical brain damage. Three hours of neurosurgery by Dr. William Butler and his team saved Rohan's life. He then spent four weeks in a coma at MGH before receiving five months of specialized treatment at Spaulding Rehabilitation Hospital, progressing enough that he regained much of his memory and personality. Doctors say it will take years of therapy before they can fully gauge the limits of Rohan's recovery. His mobility remains severely diminished, but his mind is sharp; his sense of humor, too. He returned home after his medical team and parents agreed that he might benefit from living with his family and receiving intensive outpatient therapy. He recently greeted a Globe reporter and photographer by composing a message on his whiteboard in French. Advertisement Why French? He remembers studying it in class. 'I am soon to be a French scholar,' he wrote to the amusement of his parents and guests. But the transition home has proved frightening at times. Rohan has twice experienced prolonged seizures, requiring ambulances to rush him to emergency rooms — first to Good Samaritan, the next time to MGH. When a nurse at Good Samaritan recognized him, she told his parents, 'I'm so happy to see him alive.' His mother winced, recalling their harrowing experience months earlier. Fear has haunted his parents since. One or the other constantly stays close to Rohan. One sleeps in his room, waking every three hours to turn him to prevent muscle soreness. He has a bell to ring for help, and they installed a camera to keep an eye on him. They also built an accessible bathroom and erected a wheelchair ramp to their door. Abhishek Shukla (left) and Deepika Talukdar place leg splints on their 16-year-old son, Rohan Shukla. John Tlumacki/Globe Staff His mother, who left her career as a software engineer to care for him, accompanies him four days a week as he travels for therapy in Waltham. His father, Abhishek Shukla, also a software engineer, commutes to Boston and helps when he can. Caring for Rohan demands so much attention that his parents regret the time they have lost with Naman, such as cheering for him as he travels as a pitcher for a club team, the East Coast Eagles. Yet Rohan has helped to nurture Naman. Even as Rohan yearns to reclaim his prior self — he hungers for a day when he can eat his favorite dish, his mother's chicken tacos — he finds ways to lift Naman. When Naman recently returned home dejected after a subpar pitching performance, he refused to speak to his parents about it. Rohan intervened. He snapped his fingers to grab his brother's attention and wrote on his whiteboard, 'Hey Naman don't beat yourself up.' Rohan Shukla returned home in late May, after his medical team and parents agreed that he might benefit from living with his family and receiving intensive outpatient therapy. John Tlumacki/Globe Staff Rohan's parents said after the Globe's visit, 'Rohan's spirit keeps us optimistic and going. Deep inside, we believe he's eventually going to come out of this resilient and strong and will continue to remind people that nothing is impossible.' Playing football again, though? His mother was shaken by his vision. 'I couldn't stop my tears,' she said. She never wanted him to play in the first place, but he wore her down. He wanted to be a wide receiver, to shine on the gridiron. He remembers the jersey number (81) he wore two years ago on Sharon's freshman/sophomore team, but he had no memory of his varsity number (7) last year until his parents informed him. In fact, he remembers all but nothing of the season that ultimately cost him the life he once knew. His mother asked him if he gets sad sometimes. 'Yes,' he wrote, 'because I cannot get up.' But he loves the sport. And soon, with help from his brother and friends, he will take another step in his recovery by playing a different kind of football, a game free of physical pain. A game called fantasy. Bob Hohler can be reached at
Yahoo
2 hours ago
- Yahoo
Humans may have hibernation ‘superpowers' in untapped genes, scientists say
The 'superpowers' of hibernating animals are also present in human DNA, according to a pair of recent studies that provide clues to unlocking this potential and opening the door for new diabetes and Alzheimer's treatments. Hibernating animals such as squirrels and bears exhibit incredible resilience, going long periods without food and water and withstanding near-freezing temperatures by slowing down metabolism. They avoid muscle and nerve decay and stay healthy despite massive weight fluctuations. When these animals emerge from hibernation, they appear to recover from dangerous symptoms similar to those seen in people suffering from diabetes, Alzheimer's and stroke. 'If we could regulate our genes a bit more like hibernators, maybe we could overcome type 2 diabetes the same way a hibernator returns from hibernation back to a normal metabolic state,' Elliott Ferris, an author of one of the studies, says. The research focuses on a gene cluster called the 'fat mass and obesity locus', which plays an important role in hibernators. DNA regions near the FTO locus regulate the activities of neighbouring genes, tuning them up or down. They enable hibernators to put on weight before cosying up for winter and allow them to slowly use their fat reserves throughout hibernation, researchers say. 'What's striking about this region is that it is the strongest genetic risk factor for human obesity,' says Chris Gregg, a senior author of one of the studies from the University of Utah Health. When researchers mutated the hibernator-specific gene regions in mice, they noticed changes in their metabolism and weight. Some mutations sped up weight gain while others slowed it down under specific dietary conditions. The mutations also affected the ability of mice to recover body temperature after a hibernation-like state. 'When you knock out one of these elements – this one tiny, seemingly insignificant DNA region – the activity of hundreds of genes changes,' Susan Steinwand, another author of the studies, says. Previous studies show that hibernating animals can reverse neurodegeneration, avoid muscle decay, remain healthy despite massive weight fluctuations, and show improved ageing and longevity. The latest studies suggest we possess the necessary genetic code for hibernator-like superpowers, if we can bypass some of our metabolic switches. 'This work provides a genetic framework for harnessing hibernator adaptations to understand human metabolic control,' researchers say. 'Humans already have the genetic framework,' Dr Steinwand says. 'We just need to identify the control switches for these hibernator traits.' Further studies on these genes and their surrounding DNA regions can help confer similar resilience to humans, scientists say. 'There's potentially an opportunity – by understanding these hibernation-linked mechanisms in the genome – to find strategies to intervene and help with age-related diseases,' Dr Gregg says. 'If that's hidden in the genome that we've already got, we could learn from hibernators to improve our own health.' Solve the daily Crossword


Fox News
21 hours ago
- Fox News
Christian bodybuilder reveals how fitness honors God: 'Your body is a temple'
Regular exercise is known to benefit physical and mental health — but there has been some debate about whether pursuing physical improvement could conflict with Christian principles. Some have cautioned that putting too much focus on fitness could veer into "idol worship," which is when another pursuit surpasses devotion to God. In the book "Counterfeit Gods: The Empty Promises of Money, Sex, and Power and the Only Hope that Matters," author Tim Keller defines an idol as "anything more important to you than God, anything that absorbs your heart and imagination more than God, anything you seek to give you what only God can give." According to some points of view, that could even include exercise. Others — like Hunter Sprague, a Christian bodybuilder and father of three in Texas — take a different perspective. After spending time in Christian ministry, Sprague tapped into his personal passion for exercise and strength-building to launch Monolith Movement, a coaching and mentorship platform that helps men balance faith and fitness. In an on-camera interview with Fox News Digital, Sprague described physical health as a form of spiritual stewardship, which is reflected in 1 Corinthians in the New Testament: "Your body is a temple of the Holy Spirit ... therefore honor God with your body." (See part of the interview in the video at the top of this article.) Sprague acknowledged that in Gnosticism — a set of ancient religious beliefs that emerged around the 1st and 2nd centuries AD — followers believed that the physical body and the material world "just didn't matter." "If you're going to be saved, be enlightened, you have to kind of ascend the body," he said of the belief. "It's this mindset that it's all about my heart, and my body doesn't matter." Over time, Sprague was able to strike a balance between his commitment to physical fitness and his devotion to his faith. "Our bodies matter, our physical material world matters — it was created," he said, noting that the physical form is a critical part of who we are designed to be. "That is the natural created order — if the Lord didn't desire for you to have a body, you wouldn't have one." "I think the Lord kind of used fitness to illuminate a lot of this to me," Sprague went on. "I can't just live a mental faith — there has to be some experiential power that goes along with it." "If the Lord didn't desire for you to have a body, you wouldn't have one." In his view, exercise and fitness are a form of embracing the control — the "agency" — that the Lord has given us over our bodies. "This is primarily a matter of stewardship," Sprague said. "How are you stewarding the fact that you have a functioning body? How are you stewarding the fact that you've been given all of these tools and resources and abilities?" "What are you doing with it for the benefit of others, for your benefit, as you seek to love the Lord and delight in him, and have that sense of peace and hope and resilience?" In his own personal fitness routine, Sprague said he focuses on a mix of strength training and cardio. "For a lot of people, fitness equates to just weight loss, but if you're losing weight without building muscle, you're shooting yourself in the foot," he told Fox News Digital. Strength training is "absolutely crucial" for Americans right now, the expert said, as many people are "overweight and under-muscled." Sprague spends three to four days a week in the gym lifting weights and using cable machines. "It's the hard part, it's the slow burn. It doesn't happen by accident," he said. "It's just pushing myself week after week, competing against myself." For cardio, Sprague recommends finding opportunities to keep moving and to increase daily steps. "You'll see a massive difference between 2,000 or 4,000 steps and doubling that to 8,000 or 10,000," he said. "And if you can go up from there, the more the merrier." Walking is an "easy barrier to entry," he said, and is very good for brain health and digestion. In addition to alternating between walking and sprinting, Sprague recommends finding other ways to stay active in day-to-day life. "Just more activity that's coupled with something you enjoy is really helpful," he said. In terms of nutrition, Sprague focuses on what he calls "modular eating," including a few lean proteins, fibrous vegetables and a handful of carbs. If he's trying to achieve a particular goal, he carefully tracks his food intake to get "absolute clarity" into how he's doing. When it comes to supplements, Sprague said he keeps it "very, very simple." "I do creatine and monohydrate every day. I'll utilize protein powders to reach my protein target with minimal calories." For anyone looking to honor their body and also honor the Lord, Sprague said it's important to recognize that the physical being matters, but that it will never be the main source of happiness or peace. "It's hard to be satisfied, it's hard to get to a place where you're like, 'I'm done, I made it,'" Sprague said. "There's always going to be this sense of, 'There's more to go, there's more to do.'" "My identity, my worth, my value, isn't wrapped up in what I achieve physically — rather, this process is just a joy in itself." In the pursuit of greater physical fitness, Sprague said it's essential to "notice God's goodness" in all of it. "It's a means of grace that the Lord designed endorphins for you — he designed dopamine for you," he noted. "He designed the feeling of accomplishment you get when you lift something or run a little bit farther or have a really good day with your food — that's not inconsequential." "The more you bring the Lord into this and notice His goodness in it, the better it goes." Setting specific goals and making a plan to achieve them is the most effective path to success, according to the expert. "Just get some momentum and start putting one foot in front of the other," Sprague advised. "It all comes down to time and effort. Put some pressure on yourself, set some deadlines and just go do it — because the thinking, considering and mulling it over will get you absolutely nowhere," he went on. For more Health articles, visit "And the more you bring the Lord into this and notice His goodness in it, the better it goes."